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MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Human lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-03 | MTBLS8856 | MetaboLights
MetabolomicsLipid-accumulated reactive astrocytes promote disease progression in epilepsy (Mice lipidomics)

Reactive astrocytes play an important role in neurological diseases, but their molecular and functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal lobe epilepsy (TLE) and mouse models of epilepsy, excessive lipid accumulation in astrocytes leads to the format...

2025-07-04 | MTBLS8865 | MetaboLights
UnknownAssemblages of rhizospheric and root endospheric mycobiota and their ecological associations with functional traits of rice.
Not available
S-EPMC10936437 | biostudies-literature
UnknownOn-bead DNA synthesis triggered by allosteric probe for detection of carcinoembryonic antigen.
Not available
S-EPMC9342938 | biostudies-literature
MetabolomicsAltered metabolome and microbiome features provide clues in understanding irritable bowel syndrome and depression comorbidity

Irritable bowel syndrome (IBS) is one of the functional gastrointestinal disorders characterized by chronic and/or recurrent symptoms of abdominal pain and irregular defecation. Changed gut microbiota has been proposed to mediate IBS; however, contradictory results exist, and IBS-specific microbi...

2021-12-01 | MTBLS2774 | MetaboLights
UnknownTenofovir alafenamide and tenofovir disoproxil fumarate reduce incidence of hepatocellular carcinoma in patients with chronic hepatitis B.
Not available
S-EPMC10522903 | biostudies-literature
UnknownDeacetylation of FOXP1 by HDAC7 potentiates self-renewal of mesenchymal stem cells.
Not available
S-EPMC10385979 | biostudies-literature
UnknownComparison of widefield swept-source optical coherence tomography angiography and ultra-widefield fluorescein angiography in the detection of non-perfusion areas in diabetic retinopathy.
Not available
S-EPMC12011578 | biostudies-literature
ProteomicsAn Isocaloric High-Fat Diet Improves Lifespan in Rats and Drosophila
The health effect of dietary fat has been one of the most vexing issues in the nutrition field. Few animal studies have examined the impact of high-fat diets on lifespan by controlling energy intake. In this study, we found that compared to a normal diet, an isocaloric high-fat diet (IHF) significan...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-01-06 | PXD022585 | Pride
Isocaloric High-fat diet Proteomics Lifespan 
UnknownEvaluation of genome size and phylogenetic relationships of the Saccharum complex species.
Not available
S-EPMC9582063 | biostudies-literature
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