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ProteomicsC-terminomics E. coli - C-terminal charge-reversal derivatization and parallel use of multiple proteases facilitates identification of protein C-termini by C-terminomics
The identification of protein C-termini in complex proteomes is challenging due to the poor ionization efficiency of the carboxyl group. Amidating the negatively charged C-termini with ethanolamine (EA) has been suggested to improve detection of C-terminal peptides and allows for a directed depletio...
ORGANISM(S): Escherichia coli 
2016-03-11 | PXD003342 | Pride
Cid Hcd Etd C-terminus Derivatization 
ProteomicsComparative Proteome Analysis in Schizosaccharomyces pombe identifies metabolic targets to improve protein production and secretion
Protein secretion in yeast is a complex process and its efficiency depends on a variety of parameters. We performed a comparative proteome analysis of a set of Schizosaccharomyces pombe strains producing the alpha-glucosidase maltase in increasing amounts to investigate the overall proteomic respons...
ORGANISM(S): Schizosaccharomyces pombe 
2016-08-08 | PXD002693 | Pride
Isobaric labeling 2d-lc maldi ms 5800 proteome analyzer High/low ph lc Itraq 
ProteomicsComparative Proteome Analysis in Schizosaccharomyces pombe identifies metabolic targets to improve protein production and secretion
This dataset contains additional experimental results for the determination of the effect of Fluconazole and amino acid supplementation to the NW10 strain of S. pombe. Protein secretion in yeast is a complex process and its efficiency depends on a variety of parameters. We performed a comparative p...
ORGANISM(S): Schizosaccharomyces pombe 
2016-08-08 | PXD003016 | Pride
Isobaric labeling 2d-lc maldi ms 5800 proteome analyzer High/low ph lc Itraq 
TranscriptomicsTranscriptional profiling analysis by microarray comparing the isogenic wild-type strain Bacillus thuringiensis 407 with a markerless cdgF deletion mutant was performed with exponentially growing cells in planktonic culture.
The transcriptional global profiles of the wild-type strain Bacillus thuringiensis 407 and a cdgF deletion mutant were compared after 1.5 hours of growth in an planktonic culture to analyze the effect of deletion of cdgF, which is involved in c-di-GMP signaling, on the global expression profile of B...
ORGANISM(S): Bacillus thuringiensis Bt407 
2019-07-30 | E-MTAB-8092 | biostudies-arrayexpress
MetabolomicsNontargeted and targeted metabolomics measurements of abiotic stress responses in three-week-old Arabidopsis thaliana plants' rosette leaf tissue
Nontargeted and targeted metabolomics measurements of abiotic stress responses in three-week-old Arabidopsis thaliana plants' rosette leaf tissue for Col-0 wild type plants and double/triple knockout mutants of aquaporins (pip2;1 pip2;2 and pip2;1 pip2;2 pip2;4) treated with drought, heat at differe...
2017-07-17 | MTBLS355 | MetaboLights
GenomicsGenetic landscape of pediatric Medulloblastoma
Medulloblastoma is a heterogenous disease made up of at least four distinct subtypes of disease which appear to exploit and disrupt naturally occurring developmental pathways of cellular growth and hindbrain development. To better understand the driver mutations of this disease, we performed whole g...
EGAS00001000347 | EGA
GenomicsAnalysis of translatome, truncating mutations, lncRNA, circRNA and microproteins of 80 human DCM cases and controls
The regulation of gene expression in healthy and diseased human tissues is incompletely understood and has primarily been studied on the transcriptional level. Here, we quantify the impact of translation on gene expression and annotate novel translational events in 80 human hearts. These include 65 ...
EGAS00001003263 | EGA
Genomics2013-11-19-17-24-36-breez-MB-2013-10-18-Whole_exome_DNAseq_Medulloblastoma - samples
Illumina HiSeq sequence data (with >80x coverage) were aligned to the hg19 human reference genome assembly using BWA (Li and Durbin, 2009); duplicate reads were removed from the final BAM file. No realignment or recalibration was performed. The whole exome sequencing data of 20 SHH medulloblastomas ...
EGAD00001000698 | EGA
GenomicsSHH medulloblastoma samples
Sequencing data of human SHH medulloblastoma samples
EGAS00001000607 | EGA
Genomics1fcf2848-b51f-450f-a20d-02c6d8156eb7 - samples
Dataset consists of fastq files of Ribo-seq, polyA-RNA and total RNA sequencing of 80 samples (65 DCM cases and 15 controls)
EGAD00001004394 | EGA
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