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ProteomicsC-terminomics E. coli - C-terminal charge-reversal derivatization and parallel use of multiple proteases facilitates identification of protein C-termini by C-terminomics
The identification of protein C-termini in complex proteomes is challenging due to the poor ionization efficiency of the carboxyl group. Amidating the negatively charged C-termini with ethanolamine (EA) has been suggested to improve detection of C-terminal peptides and allows for a directed depletio...
ORGANISM(S): Escherichia coli 
2016-03-11 | PXD003342 | Pride
Cid Hcd Etd C-terminus Derivatization 
TranscriptomicsHepatic acute phase proteins control innate immune responses during infection by promoting myeloid derived suppressor cell function
Acute phase proteins (APPs) are an evolutionarily conserved family of proteins produced mainly in the liver in response to infection and inflammation. Despite vast pro- and anti-inflammatory properties ascribed to individual APPs, their collective function during infections remains poorly defined. U...
ORGANISM(S): Mus musculus 
2010-06-08 | E-GEOD-22009 | biostudies-arrayexpress
TranscriptomicsThe CRE1 carbon catabolite repressor of the fungus Trichoderma reesei: a master regulator of carbon assimilation
The identification and characterization of the transcriptional regulatory networks governing the physiological behaviour and adaptation of microbial cells is a key step in understanding their behaviour. One such wide-domain regulatory circuit, essential to all cells, is carbon catabolite repression ...
ORGANISM(S): Hypocrea jecorina 
2011-06-01 | E-GEOD-21072 | biostudies-arrayexpress
UnknownGreen tea halts progression of cardiac transthyretin amyloidosis: an observational report.
Not available
S-EPMC3445797 | biostudies-literature
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