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GATA factors interact with simple DNA motifs (WGATAR) to regulate critical processes, including hematopoiesis, but very few WGATAR motifs are occupied in genomes. Given the rudimentary knowledge of mechanisms underlying this restriction, and how GATA factors establish genetic networks, we used ChIP-...
ORGANISM(S): Homo sapiens 
The nuclear scaffold/matrix provides an anchor for higher order genome structure that has both structural and functional implications. Different extraction protocols, i.e., utilizing either 25 mM LIS or 2 M NaCl, isolate somewhat different protein constituents of either the nuclear scaffold or nucl...
ORGANISM(S): Homo sapiens 
The nuclear scaffold/matrix provides an anchor for higher order genome structure that has both structural and functional implications. Different extraction protocols, i.e., utilizing either 25 mM LIS or 2 M NaCl, isolate somewhat different protein constituents of either the nuclear scaffold or nucl...
ORGANISM(S): Homo sapiens 
Abnormal trophoblast invasion is associated with the most common and most severe complications of human pregnancy. The biology of invasion, as well as the etiology of abnormal invasion remains poorly understood. The aim of this study was to characterize the transcriptome of the HTR-8/SVneo human c...
ORGANISM(S): Homo sapiens 
Coxsackieviruses B (CVBs) emerge as candidate environmental triggers for the autoimmunity against pancreatic islet β cells leading to type 1 diabetes. Persistent CVB infections in the gut and pancreas correlate with islet autoantibody seroconversion, suggesting defective antiviral control in predisp...
ORGANISM(S): Homo sapiens (Human) 
2026-05-07 | PXD070471 | Pride
Coxsackieviruses B (CVBs) emerge as candidate environmental triggers for the autoimmunity against pancreatic islet β cells leading to type 1 diabetes. Persistent CVB infections in the gut and pancreas correlate with islet autoantibody seroconversion, suggesting defective antiviral control in predisp...
ORGANISM(S): Homo sapiens (Human) 
2026-05-07 | PXD070119 | Pride
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