Sort   by:  
 Page size 
ProteomicsAnalysis of Substrate Specificity of Trypanosoma brucei OSTs by Functional Expression in Yeast
N-linked protein glycosylation is an essential and highly conserved post-translational modification in eukaryotes. The transfer of a glycan from a lipid-linked oligosaccharide (LLO) donor to asparagine residues of nascent polypeptide chains is catalyzed by the oligosaccharyltransferase (OST) in the ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2017-11-03 | PXD007215 | Pride
Lipid linked oligosaccharide specificity Oligosaccharyltransferase N-linked glycosylation Glycosylation occupancy analysis Trypanosoma brucei 
UnknownReconstitution of the lipid-linked oligosaccharide pathway for assembly of high-mannose N-glycans.
Not available
S-EPMC6472349 | biostudies-literature
ProteomicsAnalysis of the substrate specificities and reaction kinetics of the yeast oligosaccharyltransferase isoforms
Oligosaccharyltransferase (OST) catalyzes the central step in N-linked protein glycosylation, the transfer of a pre-assembled oligosaccharide from its lipid carrier onto asparagine residues of secretory proteins. The prototypic hetero-octameric OST complex from the yeast Saccharomyces cerevisiae exi...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-05-19 | PXD024590 | Pride
Site-occupancy Yeast oligosaccharyltransferase Substract specificity 
UnknownSubstrate specificity of bacterial oligosaccharyltransferase suggests a common transfer mechanism for the bacterial and eukaryotic systems.
Not available
S-EPMC1459022 | biostudies-literature
UnknownSubstrate specificity of cytoplasmic N-glycosyltransferase.
Not available
S-EPMC4148877 | biostudies-literature
UnknownLoss of specificity variants of WzxC suggest that substrate recognition is coupled with transporter opening in MOP-family flippases.
Not available
S-EPMC6181778 | biostudies-literature
UnknownAnalysis of substrate specificity of Trypanosoma brucei oligosaccharyltransferases (OSTs) by functional expression of domain-swapped chimeras in yeast.
Not available
S-EPMC5724018 | biostudies-literature
ProteomicsGlycoproteomic and proteomic alterations in SRD5A3-deficient fibroblasts
SRD5A3-CDG is a congenital disorder of glycosylation (CDG) resulting from pathogenic variants in SRD5A3 and follows an autosomal recessive inheritance pattern. The enzyme encoded by SRD5A3, polyprenal reductase, plays a crucial role in synthesizing lipid precursors essential for N-linked glycosylati...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055397 | Pride
Dolichol Lipid-linked oligosaccharide Cdg type i N-glycosylation Polyprenol 
ProteomicsDiscovery and characterization of a new class of O-linking oligosaccharyltransferase from bacteria in the Moraxellaceae family
Bacterial protein glycosylation can be mediated by oligosaccharyltransferases (OTases) that transfer a preassembled lipid-linked oligosaccharide or polysaccharide en bloc to acceptor proteins. O-linking OTases transfer O-antigen or capsular polysaccharides to the side chains of serine or threonine r...
ORGANISM(S): Moraxella osloensis 
2022-10-13 | PXD033468 | Pride
Glycosylation M. osloensis 
UnknownCytoplasmic N-glycosyltransferase of Actinobacillus pleuropneumoniae is an inverting enzyme and recognizes the NX(S/T) consensus sequence.
Not available
S-EPMC3186387 | biostudies-literature
Sort   by:  
 Page size