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ProteomicsA luciferase-fragment complementation assay to detect lipid droplet-associated protein-protein interactions
The regulation of organismic lipid storage amounts is a central goal of all organisms. Proteins associated with the dedicated lipid storage organelles, the so-called lipid droplets (LDs), are instrumental to this regulation. LD proteomes of diverse organisms have been characterized by mass spectrome...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2016-12-22 | PXD003944 | Pride
Mass spectrometry Protein-protein interaction Lipid droplet Luciferase-fragment complementation assay 
MetabolomicsDifferential interactions of dietary EPA and DHA with the gut microbiota dictate distinct metabolic outcomes in the host

Background: Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are known to modulate host physiology, but their differential interactions with the gut microbiota and consequent host metabolic effects remain poorly understood.

Methods: We employed shotgun metagenomics, untargeted met...

2026-01-31 | MTBLS13495 | MetaboLights
MetabolomicsDifferential interactions of dietary EPA and DHA with the gut microbiota dictate distinct metabolic outcomes in the host

Background: Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are known to modulate host physiology, but their differential interactions with the gut microbiota and consequent host metabolic effects remain poorly understood.

Methods: We employed shotgun metagenomics, untargeted met...

2026-01-31 | MTBLS13497 | MetaboLights
MetabolomicsMetabolic interactions of “catecholamine-cholesterol derivatives” as a potential mechanism for immunomodulation of chicken adipose tissue

In recent years, the immunomodulatory function of adipose tissue has attracted much attention; however, the mechanism of steady-state regulation of the immune microenvironment in adipose tissue remains unclear. Catecholamines (CAs) activate adipocyte surface β3-AR to promote lipid metabolism, and...

2025-07-15 | MTBLS12719 | MetaboLights
MetabolomicsMulti-omic analysis of vaginal bacteria:host immune and metabolic interactions in early adverse pregnancy outcomes

Objective

To characterise the vaginal microbiota, mucosal metabolome and host immune response in early pregnancy and investigate its relationship with adverse pregnancy outcomes, including ectopic pregnancy, within the context of pregnancies of unknown location (PUL).

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2025-03-28 | MTBLS10098 | MetaboLights
MetabolomicsExploring the interactions between polyphenols in the fermented grains of sauce-flavor Baijiu and Saccharomyces cerevisiae based on transcriptomic and metabolomic approaches
Polyphenols are abundant in the raw materials (sorghum and wheat) used for sauce-flavor Baijiu fermentation, yet their interactions with the key brewing microorganism (Saccharomyces cerevisiae), remain poorly characterized. This study employed integrated transcriptomic and metabolomic approaches to ...
2026-06-29 | MTBLS14885 | MetaboLights
UnknownData supporting beta-amyloid dimer structural transitions and protein-lipid interactions on asymmetric lipid bilayer surfaces using MD simulations on experimentally derived NMR protein structures.
Not available
S-EPMC4802547 | biostudies-literature
UnknownAn improved protein lipid overlay assay for studying lipid-protein interactions.
Not available
S-EPMC7060618 | biostudies-literature
UnknownBioDolphin as a comprehensive database of lipid-protein binding interactions.
Not available
S-EPMC11618342 | biostudies-literature
UnknownTemperature-dependence of membrane protein-lipid interactions in membranes.
Not available
S-EPMC12204147 | biostudies-literature
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