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TranscriptomicsTumor gene expression analysis - PI3K Inhibition by Copanlisib in Relapsed or Refractory Indolent Lymphoma
Of the 142 patients enrolled in Study CHRONOS-1, an open-label, single-arm, Phase II study evaluating the efficacy and safety of single-agent copanlisib in patients with relapsed or refractory, indolent B-cell lymphoma (NCT01660451; Part B), 96 archival formalin-fixed paraffin-embedded tumor tissues...
ORGANISM(S): Homo sapiens 
2017-12-01 | E-MTAB-6088 | biostudies-arrayexpress
TranscriptomicsThe amniotic fluid transcriptome: a source of novel information about human fetal development
Amniotic fluid (AF) is a complex biological material that provides a unique window into the developing human. Residual AF supernatant contains cell-free fetal RNA. The objective of this study was to develop an understanding of the AF core transcriptome by identifying the transcripts ubiquitously pre...
ORGANISM(S): Homo sapiens 
2012-01-11 | E-GEOD-33168 | biostudies-arrayexpress
GenomicResearch Program on Genes, Environment and Health (RPGEH)

The Kaiser Permanente Research Program on Genes, Environment, and Health (RPGEH) is a resource developed to facilitate research on genetic and environmental factors on common diseases and healthy aging. The RPGEH resource links biospecimens, health surveys, and comprehensive electronic medical re...

phs000788 | dbGaP
TranscriptomicsMaternal obesity affects fetal neurodevelopmental and metabolic gene expression
To investigate fetal gene expression in obese compared to lean women in the second trimester, by performing global gene expression analysis of amniotic fluid (AF) cell-free RNA Analysis of paired data from obese cases and lean controls revealed differential expression of 205 genes. Functional analys...
ORGANISM(S): Homo sapiens 
2013-07-04 | E-GEOD-48521 | biostudies-arrayexpress
TranscriptomicsGlobal Gene Expression Analysis of Term Amniotic Fluid Cell-Free Fetal RNA
The objective of this study was to identify the tissue expression patterns and biological pathways enriched in term amniotic fluid cell-free fetal RNA by comparing functional genomic analyses of term and second-trimester amniotic fluid supernatants. There were 2,871 significantly differentially regu...
ORGANISM(S): Homo sapiens 
2013-04-23 | E-GEOD-46286 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human hepatocellular carcinoma cell line Huh7 and immortalized hepatocyte cell line THLE5B treated with experimental compound AD80, Sorafenib, and vehicle for 24 hours
To delineate the transcriptomic changes induced by AD80 relative to sorafenib, we performed RNA-sequencing (RNA-seq) on HUH7 and THLE5B cells treated for 24 hours with either DMSO, sorafenib, or AD80 near respective growth inhibitory GI50 values. HUH7 cells were plated in 6 well plates, treated for ...
ORGANISM(S): Homo sapiens 
2019-08-02 | E-MTAB-7847 | biostudies-arrayexpress
TranscriptomicsRNA-Seq and expression microarray highlight different aspects of the fetal amniotic fluid transcriptome [microarray]
The second trimester fetal transcriptome can be assessed based on cell-free RNA found within the amniotic fluid supernatant. The objective of this study was to compare the suitability of two technologies for profiling the human fetal transcriptome: RNA-Seq and expression microarray. Comparisons were...
ORGANISM(S): Homo sapiens 
2014-05-27 | E-GEOD-49891 | biostudies-arrayexpress
UnknownBrain and circulating EV proteome signatures in schizophrenia as prognostic markers for age-related dementia.
Not available
S-EPMC12905883 | biostudies-literature
TranscriptomicsGlobal gene expression analysis of amniotic fluid cell-free RNA from recipient twins with twin-twin transfusion syndrome [Set 2]
To understand the biological pathways involved in twin-twin transfusion syndrome (TTTS) by performing global gene expression analysis of amniotic fluid (AF) cell-free RNA Analysis of paired data from TTTS cases and controls revealed differential expression of 801 genes, which were significantly enri...
ORGANISM(S): Homo sapiens 
2013-05-28 | E-GEOD-47393 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of amniotic fluid cell-free RNA from recipient twins with twin-twin transfusion syndrome [Set 1]
To understand the biological pathways involved in twin-twin transfusion syndrome (TTTS) by performing global gene expression analysis of amniotic fluid (AF) cell-free RNA Analysis of paired data from TTTS cases and controls revealed differential expression of 801 genes, which were significantly enri...
ORGANISM(S): Homo sapiens 
2013-05-28 | E-GEOD-47392 | biostudies-arrayexpress
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