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ProteomicsIntegrated Single-Cell Proteomics Analysis on an Active Matrix Digital Microfluidic Chip
We introduce and implement a comprehensive single-cell proteomics sample pre-treatment solution based on an active matrix digital microfluidics chip(AM-DMF-SCP). This platform accommodates high-throughput single-cell isolation and seamless, non-destructive sample pre-treatment, characterized by its ...
ORGANISM(S): Homo Sapiens 
2024-04-15 | PXD048434 |
UnknownAM-DMF-SCP: Integrated Single-Cell Proteomics Analysis on an Active Matrix Digital Microfluidic Chip.
Not available
S-EPMC11134390 | biostudies-literature
ProteomicsIdentification of TTC29 protein partners in mouse testis
We previously identified gene variants in TTC29 that induce human male infertility due to asthenozoospermia and MMAF phenotype (Lores et al. Am J hum genet 2019). By means of CRISPR/Cas9 mutagenesis we demonstrated that the orthologous TTC29 protein in mouse also constitute a flagellar protein that...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-06 | PXD039854 | Pride
Co-immunoprecipitation Asthenozoospermia Male infertility Ttc29 Crispr mouse model 
ProteomicsNew Insights into Heat Responses in Grape Leaves through Combined Phosphoproteomic and Acetylproteomic Analyses
Heat stress is a serious and widespread threat to the quality and yield of many crops, including grape (Vitis vinifera), which is cultivated worldwide. Here, we conducted phosphoproteomic and acetylproteomic analyses of leaves from grape cultivated in four distinct temperature regimes. The phosphory...
ORGANISM(S): Vitis vinifera (Grape) 
2019-11-13 | PXD014090 | Pride
Heat Acetylproteome Grape Phosphoproteome 
MetabolomicsLactation-related metabolic mechanism investigated based on mammary gland metabolomics and 4 biofluids’ metabolomics relationships in dairy cows

BACKGROUND: Lactation is extremely important for dairy cows; however, the understanding of the underlying metabolic mechanisms is very limited. This study was conducted to investigate the inherent metabolic patterns during lactation using the overall biofluid metabolomics and the...

2018-03-16 | MTBLS411 | MetaboLights
UnknownNonlinear relationship between sleep midpoint and osteoarthritis: a cross-sectional study in US adults.
Not available
S-EPMC12923419 | biostudies-literature
MetabolomicsIntegrated multi-omics analysis and experimental verification reveal the involvement of the PI3K/Akt signaling pathway in myometrial fibrosis of adenomyosis.

This analysis established comprehensive metabolomic profiles of adenomyosis patients and revealed widespread alterations in the metabolome within normal and fibrotic myometrium. Integrated analysis shown significant associations between metabolomic data and fibrosis . This study is the first to d...

2025-05-12 | MTBLS11965 | MetaboLights
MetabolomicsModerate salinity restricts the transformation depth of norfloxacin by halotolerant Chlorella sp. AMC-2: Physiological adaptation and metabolic reprogramming
Despite increasing application of microalgae for antibiotic-contaminated aquaculture wastewater treatment, how salinity regulates antibiotic transformation depth and cellular adaptation remains unclear. This study combined salinity-gradient cultivation, process partitioning, transformation-product p...
2026-10-01 | MTBLS15888 | MetaboLights
UnknownDetection of Frog Virus 3 by Integrating RPA-CRISPR/Cas12a-SPM with Deep Learning.
Not available
S-EPMC10500685 | biostudies-literature
UnknownCas12a-assisted RTF-EXPAR for accurate, rapid and simple detection of SARS-CoV-2 RNA.
Not available
S-EPMC9444317 | biostudies-literature
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