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ProteomicsIdentification of TTC29 protein partners in mouse testis
We previously identified gene variants in TTC29 that induce human male infertility due to asthenozoospermia and MMAF phenotype (Lores et al. Am J hum genet 2019). By means of CRISPR/Cas9 mutagenesis we demonstrated that the orthologous TTC29 protein in mouse also constitute a flagellar protein that...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-06 | PXD039854 | Pride
Co-immunoprecipitation Asthenozoospermia Male infertility Ttc29 Crispr mouse model 
UnknownNovel biallelic mutations in TTC29 cause asthenoteratospermia and male infertility.
Not available
S-EPMC9747556 | biostudies-literature
UnknownBi-allelic Mutations in TTC29 Cause Male Subfertility with Asthenoteratospermia in Humans and Mice.
Not available
S-EPMC6904824 | biostudies-literature
UnknownMutations in TTC29, Encoding an Evolutionarily Conserved Axonemal Protein, Result in Asthenozoospermia and Male Infertility.
Not available
S-EPMC6904810 | biostudies-literature
UnknownNovel axonemal protein ZMYND12 interacts with TTC29 and DNAH1, and is required for male fertility and flagellum function.
Not available
S-EPMC10629824 | biostudies-literature
ProteomicsEnrichment and mass spectrometry analysis of TbTAX-1-interacting or TbTTC29-interacting proteins by co-immunoprecipitation
Study of Trypanosoma ZMYND12’s ortholog (TbTAX-1) confirmed an axonemal localization of the protein and knockdown of TbTAX-1 using RNAi induced dramatic flagellar motility defects as observed in human. Co-immunoprecipitation assays and ultra-structure expansion microscopy in Trypanosoma brucei then ...
ORGANISM(S): Trypanosoma brucei 
2023-11-01 | PXD039470 | Pride
Trypanosoma Co-immunoprecipitations Flagellar motility Zmynd12 
UnknownGene Expression Profiling in the Striatum of Per2 KO Mice Exhibiting More Vulnerable Responses against Methamphetamine.
Not available
S-EPMC7921858 | biostudies-literature
UnknownIntegrating Genome-Wide CNVs Into QTLs and High Confidence GWAScore Regions Identified Positional Candidates for Sheep Economic Traits.
Not available
S-EPMC7325882 | biostudies-literature
UnknownZMYND12 serves as an IDAd subunit that is essential for sperm motility in mice.
Not available
S-EPMC11335240 | biostudies-literature
UnknownGenome-Wide DNA Methylation Analysis and Functional Validation of Litter Size Traits in Jining Grey Goats.
Not available
S-EPMC10970512 | biostudies-literature
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