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TranscriptomicsExpression data from prostate cancer cell lines C4-2B (enzalutamide sensitive) and C4-2B-MDVR (enzalutamide resistant) cells
Prostate cancer C4-2B cells were cultured in enzalutamide in a dose-escalation manner. After sixty passages cells were resistant to enzalutamide, with a specific sets of genes been deregulated. We performed global gene expression analysis by cDNA microarrays to identify genes responsible for enzalut...
ORGANISM(S): Homo sapiens 
2015-04-09 | E-GEOD-64143 | biostudies-arrayexpress
UnknownCu2+ Release from Polylactic Acid Coating on Titanium Reduces Bone Implant-Related Infection.
Not available
S-EPMC9225639 | biostudies-literature
ProteomicsProteostasis perturbation of N-Myc by HSP70 inhibition improves treatment in neuroendocrine prostate cancer
N-Myc is a key driver of neuroendocrine tumors, such as neuroblastoma and neuroendocrine prostate cancer. However, N-Myc is considered undruggable because it lacks clear binding sites for small molecules. One potential way to circumvent this challenge is to identify and target the protein homeostasi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-12-08 | MSV000093611 | MassIVE
UnknownHistone modifications and Sp1 promote GPR160 expression in bone cancer pain within rodent models
Not available
S-SCDT-10_1038-S44319-024-00292-6 | biostudies-other
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