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TranscriptomicsGenome-wide Profiling of DNA Replication Timing in pombe.
DNA replication is initiated at multiple sites or origins enriched with AT-rich sequences at various times during the S-phase. While current studies of genome-wide DNA replication profiles have focused on the timing of replication and the location of origins, the efficiency of replication/firing at...
ORGANISM(S): Schizosaccharomyces pombe 
2007-08-14 | E-GEOD-6977 | biostudies-arrayexpress
GenomicsIntegrative model of genomic factors for determining binding site selection by estrogen receptor alpha in MCF-7 cancer cells
Using the estrogen receptor alpha (ERalpha) as a model ligand inducible transcription factor, we sought to explicitly define parameters that determine transcription factor binding site selection on a genomic scale in an inducible system that minimizes confounding chromatin effects by the transcripti...
ORGANISM(S): Homo sapiens 
2011-01-04 | E-GEOD-23701 | biostudies-arrayexpress
GenomicsIntegrative model of genomic factors for determining binding site selection by estrogen receptor alpha in MCF-7 cancer cells
Using the estrogen receptor alpha (ERalpha) as a model ligand inducible transcription factor, we sought to explicitly define parameters that determine transcription factor binding site selection on a genomic scale in an inducible system that minimizes confounding chromatin effects by the transcripti...
ORGANISM(S): Homo sapiens 
2011-01-25 | E-GEOD-26831 | biostudies-arrayexpress
TranscriptomicsChromosome as oncogenic organizer: functional consequences of structural mutations in breast cancer (RNA-Seq)
Chromosomal structural mutations play an important role in determining the transcriptional landscape of human breast cancers. To assess the nature of these structural mutations, we analyzed a representative sampling of the major types of breast tumor samples for detailed structural mutations using p...
ORGANISM(S): Homo sapiens 
2014-07-01 | E-GEOD-57914 | biostudies-arrayexpress
TranscriptomicsPPARg dependent expression changes during differentiation of 3T3L1 cell into adipocytes
We profiled PPARg dependent gene expression changes during differntiation of 3T3L1 cell using PPARg siRNA 3T3-L1 (Pre-adipocyte) cell line was induced to differentiate using standard adipocyte differentiation media (IBMX, Dex and Insulin) 48hrs post-confluency. RNA was harvested at day -2 (confluent...
ORGANISM(S): Mus musculus 
2010-04-08 | E-GEOD-12929 | biostudies-arrayexpress
TranscriptomicsRNA-sequencing based analysis of Listeria monocytogenes 10403S::ΔBCHL Prha-sigH and ΔBCHL Prha
In this study, RNA-seq was used to compare the transcriptomes of Listeria monocytogenes 10403S::ΔBCHL Prha-sigH and ΔBCHL Prha. RNA-seq was performed on ΔBCHL Prha-sigH and ΔBCHL Prha RNA samples representing three independent biological replicates at log phase in Brain Heart Infusion (BHI) b...
ORGANISM(S): Listeria monocytogenes 10403S 
2016-02-11 | E-GEOD-73008 | biostudies-arrayexpress
UnknownMulticentre prospective cohort study of body mass index and postoperative complications following gastrointestinal surgery.
Not available
S-EPMC4973675 | biostudies-literature
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