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Vitamin K epoxide reductases (VKOR) constitute a major family of integral membrane thiol oxidoreductases. In humans, VKOR sustains blood coagulation and bone mineralization through the vitamin K cycle. Previous chemical models assumed that the catalysis of human VKOR (hVKOR) starts from a fully redu...
ORGANISM(S): Homo sapiens (Human) 
2020-12-03 | PXD020676 | Pride
Analysis of the transcriptional effects of pGAL1-MKS1, pGAL1-NNK1, and pGAL1-FMP48 overexpression. BY4700 gal1::NAT ura3delta0 S. cerevisiae cells carrying a [pGAL1-MKS1-HA, URA3, CEN], [pGAL1-NNK1-HA, URA3, CEN], or [pGAL1-FMP48-HA, URA3, CEN] plasmid, or empty vector BG1805, were grown to early lo...
ORGANISM(S): Saccharomyces cerevisiae 
Haemaphysalis longicornis Neumann, a tick of public health and veterinary importance, spend the major part of their life cycle off-host, especially the adult host-seeking period. Thus, they have to contend with prolonged starvation (sometimes for an extended period of 1-2 years). Here, we investigat...
ORGANISM(S): Haemaphysalis Longicornis 
2022-02-10 | PXD031596 |
Tick saliva, an essential chemical secretion of the tick salivary gland, is indispensable for tick survival owing to the physiological influence it exerts on the host defense mechanisms via the instrumentality of its cocktail of pharmacologically active molecules (proteins and peptides).Here, we per...
ORGANISM(S): Haemaphysalis Longicornis 
2021-12-14 | PXD028182 |
The dynamic changes of all proteins in the kidney of mice infected with Babesia were studied by using dia quantitative proteomics technology, and the regulation strategy of proteins in the kidney of mice infected with Babesia was discussed.
ORGANISM(S): Mus Musculus 
2021-01-27 | PXD023863 |
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