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ProteomicsComparative gene and protein expression profile of olfactory ensheathing cells from olfactory bulb and olfactory mucosa
Olfactory ensheathing cells are one of the few central nervous system regenerative cells discovered so far. It is characterized by its lifelong nerve regeneration function, and it can also release a variety of neurotrophic factors and neural adhesion molecules. It is considered to be the glial cell ...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-16 | PXD024046 | Pride
Olfactory ensheathing cells (oecs)  olfactory bulb (ob)  olfactory mucosa (om)  gene  protein  gene ontology (go)  kyoto encyclopedia of genes and genomes (kegg)  molecular function  cellular component  biological process 
ProteomicsIn-situ Click Reaction Coupled with Quantitative Proteomics for Identification of Protein Targets of Catechol Estrogens
Catechol estrogens (CEs) are metabolic electrophiles that actively undergo covalent interaction with cellular proteins, influencing molecular function. There is no feasible method to identify their binders in a living system. Herein, we developed a click chemistry-based approach using ethinylestradi...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-28 | PXD009657 | Pride
Post translational modification Metabolites Proteomics Electrophiles Dimethyl labeling Lc/ms Catechol estrogens Oxidative stress Click chemistry Redox modification 
UnknownQuantum Spin Detection in Microfiltration Immunoassays for Ultrasensitive and High-Throughput Diagnostics.
Not available
S-EPMC12921671 | biostudies-literature
TranscriptomicsLiver gene expression profiles of interferon therapy in chronic hepatitis B Patients (mRNA)
With 350 million carriers worldwide who may suffer from serious sequelae, including hepatocellular carcinoma, chronic hepatitis B virus (CHB) infection remains an important health issue. Current antiviral therapies hardly eradicate the virus. Therefore, there are still imperative need to develop new...
ORGANISM(S): Homo sapiens 
2017-02-09 | E-GEOD-66698 | biostudies-arrayexpress
UnknownNeoadjuvant Chemoradiotherapy Followed by Surgery Versus Surgery Alone for Locally Advanced Squamous Cell Carcinoma of the Esophagus (NEOCRTEC5010): A Phase III Multicenter, Randomized, Open-Label Clinical Trial.
Not available
S-EPMC6145832 | biostudies-literature
UnknownThe spleen-strengthening and liver-draining herbal formula treatment of non-alcoholic fatty liver disease by regulation of intestinal flora in clinical trial.
Not available
S-EPMC9892935 | biostudies-literature
UnknownAltered brain complexity in first-episode antipsychotic-naive patients with schizophrenia: A whole-brain voxel-wise study.
Not available
S-EPMC11525771 | biostudies-literature
UnknownCellular Mechanisms Underlying B Cell Abnormalities in Patients With Gain-of-Function Mutations in the PIK3CD Gene.
Not available
S-EPMC9253290 | biostudies-literature
ProteomicsQuantitative proteomics and bioinformatics analyses reveal the mechanism of pan-aurora kinase inhibitor tozasertib in neuroblastoma
Neuroblastoma is the third most common pediatric cancer and is responsible for approximately 15% of all childhood cancer deaths (Maris & Matthay, 1999). In our analysis, we found that poor patient survival with increasing mRNA expression level of AURKA and AURKB in Mycn-amplified neuroblastoma. In t...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2019-09-30 | PXD007640 | Pride
Neuroblastoma/ tozasertib/ itraq/ metabolite/ aurora kinase inhibitor. 
ProteomicsProteomic analysis of 442 clinical plasma samples from healthy donors and COVID-19 covalescent patients
In this study, we collected plasma samples from 22 healthy controls (HC group), 43 hospitalized patients (HO group), 196 convalescent patients 6 months after COVID-19 infection (first follow-up, F1 group), and 181 convalescent patients 12 months after COVID-19 infection (second follow-up, F2 group)....
ORGANISM(S): Homo Sapiens 
2024-08-02 | PXD054533 |
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