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MetabolomicsAltered metabolome and microbiome features provide clues in understanding irritable bowel syndrome and depression comorbidity

Irritable bowel syndrome (IBS) is one of the functional gastrointestinal disorders characterized by chronic and/or recurrent symptoms of abdominal pain and irregular defecation. Changed gut microbiota has been proposed to mediate IBS; however, contradictory results exist, and IBS-specific microbi...

2021-12-01 | MTBLS2774 | MetaboLights
MetabolomicsTranscript variants of long-chain acyl-CoA synthase 1 have distinct roles in sheep lipid metabolism
Mutton has recently been identified to be a consumer favorite, and intermuscular fat is the key factor in determining meat tenderness. Long-chain acyl-CoA synthetase 1 (ACSL1) is a vital subtype of the ACSL family that is involved in the synthesis of lipids from acyl-CoA and the oxidation of fatty a...
2023-02-06 | MTBLS5808 | MetaboLights
UnknownFruquintinib inhibits VEGF/VEGFR2 axis of choroidal endothelial cells and M1-type macrophages to protect against mouse laser-induced choroidal neovascularization.
Not available
S-EPMC7695853 | biostudies-literature
UnknownSpatial transcriptomics analysis of esophageal squamous precancerous lesions and their progression to esophageal cancer.
Not available
S-EPMC10409784 | biostudies-literature
UnknownLTCONS_00014107-miR-29b-2-3p-GPR37 axis promotes heat stimulation induced esophageal carcinogenesis.
Not available
S-EPMC12619460 | biostudies-literature
UnknownExplainable ResNet-long short-term memory model for the classification of bowel sounds frequency based on multifeature fusion.
Not available
S-EPMC12484921 | biostudies-literature
UnknownCDK15 promotes colorectal cancer progression via phosphorylating PAK4 and regulating β-catenin/ MEK-ERK signaling pathway.
Not available
S-EPMC8738751 | biostudies-literature
UnknownRevisiting the Potency of Tbx2 Expression in Transforming Outer Hair Cells into Inner Hair Cells at Multiple Ages In Vivo.
Not available
S-EPMC11154855 | biostudies-literature
ProteomicsThe proteome and phosphorylproteome of human early erythropoiesis
In order to revealed the multiple protein functional modules and kinases networks of human early erythropoiesis. We isolated the CD34+ cells drived from Human umbilical cord blood samples and induced to undergo erythropoiesis in vitro. Then, the cultured erythroid cells were sorted with FACS and sam...
ORGANISM(S): Homo Sapiens 
2022-08-03 | PXD035785 |
ProteomicsOlfactory bulb proteomics of CMS-treated rats
We used a chronic mild stress (CMS) protocol to separate susceptible-depression, susceptible-anxiety and insusceptible rat subgroups. Differential proteomes in the olfactory bulb were analyzed based on isobaric tags for relative and absolute quantitation (iTRAQ) labeling combined with mass spectrome...
ORGANISM(S): Rattus Norvegicus 
2021-04-12 | PXD023766 |
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