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ProteomicsDual-Optimized Surface Hydrophobicity and Rigidity Determines Protein Corona Absorption and Composition on Orally Delivered Nanoparticles Treating Colitis
Disease-specific protein corona adsorbed on nanocarriers critically determines their in vivo delivery efficiency. Given that macrophages can orchestrate inflammation resolution and mucosa repair, they are regarded as promising therapeutic targets in colitis. Here, we reveal that by altering the phys...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-01-21 | PXD071116 | Pride
Colitis Rigidity Hydrophobicity Oral Disease-specific protein corona 
ProteomicsDual-Optimized Surface Hydrophobicity and Rigidity Determines Protein Corona Absorption and Composition on Orally Delivered Nanoparticles Treating Colitis
Disease-specific protein corona adsorbed on nanocarriers critically determines their in vivo delivery efficiency. Given that macrophages can orchestrate inflammation resolution and mucosa repair, they are regarded as promising therapeutic targets in colitis. Here, we reveal that by altering the phys...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-01-21 | PXD071199 | Pride
Colitis Rigidity Hydrophobicity Oral Disease-specific protein corona 
no omics definedChromatin immunoprecipitation of human breast cancer cell line MCF-7 treated with 17beta-estradiol
ChIP-DSL experiments using ER alpha antibody on v1 20k promoter array
ORGANISM(S): Homo sapiens 
2007-03-31 | E-MEXP-984 | biostudies-arrayexpress
no omics definedTranscription profiling of human MCF7 estradiol treated cells sampled at 0h, 3h, 6h, 12h, 24h after treatment identifies an extensive ER-alpha binding program on human gene promoters
Gene expression experiments using the Illumina Human Ref8 whole genome expression array system. MCF7 cells were treated with estradiol and then used for expression experiments at specific timepoints after treatment (0h, 3h, 6h, 12h, 24h).
ORGANISM(S): Homo sapiens 
2007-04-01 | E-TABM-231 | biostudies-arrayexpress
ProteomicsProteomic analysis of eelgrass seed germination
We analyzed the features of proteome profiling of eelgrass seed germination stimulated by low salinity based on 4D lable-free proteomic analysis. The molecular mechanism of eelgrass seed germination kinetics revealed in this study is of great significance to the study of seagrass seed biology.
ORGANISM(S): Zostera Marina 
2023-05-18 | PXD042350 |
ProteomicsProlyl Hydroxylase Substrate Adenylosuccinate Lyase Is An Oncogenic Driver In Triple Negative Breast Cancer
Protein hydroxylation extensively regulates cellular signaling by affecting protein stability, protein-protein interaction and protein activity, and its dysregulation contributes to the pathogenesis of various diseases including cancers. However, because of the transient nature of the enzyme-substra...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-10-02 | MSV000086231 | MassIVE
ProteomicsTo explore the binding protein of HKDC1 by IP-MS
We used Hep3B cells expressing Flag tagged HKDC1 to explore the binding protein of HKDC1 by IP-MS
ORGANISM(S): Homo Sapiens 
2023-11-29 | PXD047388 |
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