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MetabolomicsLaser-assisted rapid evaporative ionisation mass spectrometry (LA-REIMS) as a metabolomics platform in cervical cancer screening

BACKGROUND: The introduction of high-risk human papillomavirus (hrHPV) testing as part of primary cervical screening is anticipated to improve sensitivity, but also the number of women who will screen positive. Reflex cytology is the preferred triage test in most settings but ha...

2022-02-15 | MTBLS1371 | MetaboLights
ProteomicsBidirectional Control of Coronary Vascular Resistance by Eicosanoids via a Novel GPCR
Arachidonic acid metabolites epoxyeicosatrienoates (EETs) and hydroxyeicosatetraenoates (HETEs) are important regulators of myocardial blood flow and coronary vascular resistance (CVR), but their mechanisms of action are not fully understood. We identified G protein-coupled receptor 39 (GPR39) as a ...
ORGANISM(S): Mus musculus (Mouse) 
2022-04-13 | PXD013952 | Pride
Proteomics Eicosanoids G-coupled receptor 39 Microvascular smooth muscle cell Cardiovascular disease Photoactive cross-linking 
UnknownIntegrative small and long RNA omics analysis of human healing and nonhealing wounds discovers cooperating microRNAs as therapeutic targets.
Not available
S-EPMC9374442 | biostudies-literature
TranscriptomicsIFN-γ Upregulates Survivin and Ifi202 Expression to Induce Survival and Proliferation of Tumor-Specific T Cells
Transcriptional profiling of mouse tumor-specific cytotoxic T lymphocytes (CTL) comparing activation-induced gene expression profiles induced by tumor-specific antigen (Ag) and CD3 mAb. CTLs were stimulated with either Ag or CD3 mAb for 3 and 24 h, respectively. The stimulated CTLs were compared to ...
ORGANISM(S): Mus musculus 
2010-12-03 | E-GEOD-22890 | biostudies-arrayexpress
TranscriptomicsA gene-expression oligo microarray for the three developmental stages of Ichthyophthirius multifiliis
The protozoan Ichthyophthirius multifiliis (Ich) is a eukaryotic ciliate parasite of freshwater fish. Ich causes ichthyophthiriosis or ‘white spot disease’ characterized by white cysts covering the host skin and gills. The parasite is responsible for high mortalities and severe economic losses to f...
ORGANISM(S): Ichthyophthirius multifiliis 
2011-09-30 | E-GEOD-18556 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation and transcription of mouse liver in the presence or absence of exogenous glucocorticoid to identify direct targets of the glucocorticoid receptor
The purpose of this study was to identify direct targets of the glucocorticoid receptor (GR) using an orthogonal analysis. An expression study of mouse livers in the presence or absence of exogenous glucocorticoid complemented a genome-wide location analysis on chromatin from the same livers. Thes...
ORGANISM(S): Mus musculus 
2007-09-14 | E-CBIL-38 | biostudies-arrayexpress
TranscriptomicsA gene-expression oligo microarray for two serial passages of Ichthyophthirius multifiliis
The protozoan Ichthyophthirius multifiliis (Ich) is a eukaryotic ciliate parasite of freshwater fish. Ich causes ichthyophthiriosis or ‘white spot disease’ characterized by white cysts covering the host skin and gills. The parasite is responsible for high mortalities and severe economic losses to f...
ORGANISM(S): Ichthyophthirius multifiliis 
2011-09-30 | E-GEOD-22466 | biostudies-arrayexpress
ProteomicsNeuronal GPCR NMUR-1 regulates energy homeostasis in response to pathogen infection in Caenorhabditis elegans
The neuronal G protein-coupled receptor NMUR-1, a homolog to the mammalian neuromedin U receptor, has been implicated in the specificity of Caenorhabditis elegans innate immune response against pathogen infections. NMUR-1 controls C. elegans transcription activity by regulating transcription factors...
ORGANISM(S): Caenorhabditis elegans 
2025-10-02 | PXD045826 | Pride
Caenorhabditis elegans F1fo atp synthase Immunity Pathogen infection G-protein coupled receptors Nmur-1 
MetabolomicsSexual dimorphism in the gonad lipidome of blue mussels (Mytilus sp.): New insights from a global lipidomics approach

Blue mussels (Mytilus sp.) are an economically important species for European aquaculture. Their importance as a food source is expected to increase in the coming net-zero society due to their low environmental footprint; however, their production is affected by anthropogenic stressors and climat...

2024-11-08 | MTBLS8492 | MetaboLights
ProteomicsThe GCN-2/eIF-2α/ATF-4 signaling pathway regulates C. elegans defense against pathogen infection
In response to external or endogenous insults, eukaryotic cells can activate a common adaptive pathway called the integrated stress response (ISR). The ISR reduces global protein translation but upregulates the expression of stress response proteins to either restore cellular homeostasis or, in case...
ORGANISM(S): Caenorhabditis elegans 
2025-10-01 | PXD058186 | Pride
Atf4 Collagens Gcn2 Mitochondrial electron transport C. elegans Bacterial infection Eif2α Ribosomal proteins Integrated stress response 
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