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UnknownIdentification and Functional Exploration of BraGASA Genes Reveal Their Potential Roles in Drought Stress Tolerance and Sexual Reproduction in Brassica rapa L. ssp. pekinensis.
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S-EPMC11395553 | biostudies-literature
ProteomicsChromatin bound O-GlcNAc proteins related to stress response and transcriptional regulation.
O-GlcNAcylation performs a critical role in regulating stress response program and cellular homeostasis. However, systematic studies of O-GlcNAc regulated genotoxic stress-responsive transcriptional reprograming have been limited. The GalNAz metabolic labeled global chromatin-associated proteins wer...
ORGANISM(S): Homo Sapiens 
PXD016713 |
ProteomicsFOXA1 O-GlcNAcylation-mediated transcriptional switch governs metastasis capacity in breast cancer
The forkhead protein FOXA1 has been found to play a critical role in orchestrating hormonal-signaling network and to function as a pioneer factor to regulate breast-specific gene expression,However, whether interplay between O-GlcNAcylation and FOXA1 affects the genome-wide transcriptional activity ...
ORGANISM(S): Homo Sapiens 
2022-12-21 | PXD039019 |
ProteomicsO-GlcNAcylation elevates topoisomerase IIα catalytic activity: a role in the chemotherapy resistance of breast cancer
DNA topoisomerase IIα (TOP2A) plays a vital role in replication and cell division by catalytically altering DNA topology. It is a prominent target for anticancer drugs. However, it is currently unknown whether TOP2A is O-GlcNAc-modified, and the mechanism by which interplay between TOP2A and O-GlcNA...
ORGANISM(S): Homo Sapiens 
PXD041284 |
ProteomicsMSRefine: comprehensive evaluation of the data-dependent LC–MS/MS workflow
There are four datasets in this paper, representing different sample types (plasma and tissue), different sample loading amounts, different chromatographic conditions and different mass spectrometers.
ORGANISM(S): Rattus Rattus Homo Sapiens Saccharomyces Cerevisiae 
PXD035468 |
ProteomicsChromatin-associated OGT promotes hepatocellular carcinoma malignancy via activating ZNF263
OGT, the only facilitator which attaches the monosaccharide to many oncogenic factors or tumor suppressors, has been suggested to play an influential role in tumorigenesis and metastasis of HCC. OGT interactome analyses indicates that disordered OGT may serve as a hub protein to activate the buildin...
ORGANISM(S): Homo Sapiens 
2023-01-12 | PXD039365 |
ProteomicsNCI60 proteome by PCT-SWATH - Quantitative Proteome Landscape of the NCI-60 Cancer Cell Lines
We obtained quantitative analysis of the NCI-60 cell panels using pressure cycling technology (PCT) and SWATH-MS. Each cell was analyzed in duplicate. The data were analyzed using a cell line SWATH assay library and OpenSWATH, followed by SWATH-expert refinement.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-07-29 | MSV000085848 | MassIVE
ProteomicsHigher-energy collisional dissociation mass spectrometry fragmentation in cancer cells
mass spectrometric analysis of monosaccharide in cancer cells
ORGANISM(S): Homo Sapiens 
PXD069643 |
ProteomicsTissue-Characteristic Expression of Mouse Proteome
264 DDA files corresponding to 36 mouse organs; PulseDIA data profiling of 41 male mouse organs and nine pairs of organs
ORGANISM(S): Mus Musculus 
PXD036255 |
ProteomicsSILAC-based quantitative mass spectrometry analysis of RPA1-containing protein complex
SILAC-based quantitative mass spectrometry analysis of RPA1-containing protein complex
ORGANISM(S): Homo Sapiens 
PXD028105 |
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