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ProteomicsGinsenoside Rb1 blocked mitochondrial reverse electron transfer-derived ROS production and protected cardiomyocytes from ischemia/reperfusion injury through reversibly inhibiting mitochondrial complex I
The management of cardiac ischemic injury has been challenged by ischemia and reperfusion (I/R) injury. Reactive oxygen species (ROS) generated from mitochondrial reverse electron transport (RET) during the early phase of reperfusion is considered to be the initiating cause for ischemia and reperfus...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-08 | PXD011414 | Pride
Rb1 Cardiomyocytes Lc-ms/ms Ros Proteome 
ProteomicsThe outer membrane protein of Riemerella anatipestifer YM strain interacting with duck vitronectin was screened by pull-down assay sequencing by mass spectrometry and search for complement escape related protein of Riemerella anatipestifer YM strain.
Riemerella anatipestifer can cause infectious serositis in ducklings with high mortality. Vitronectin acts as a complement regulator and plays a role in the terminal pathway of complement activation. It is a widely used strategy for Gram-negative bacteria to capture vitronectin to the surface of bac...
ORGANISM(S): Riemerella Anatipestifer Ra-ym 
2023-02-01 | PXD039753 |
ProteomicsMolecular characterization of advanced colorectal cancer using serum proteomics and metabolomics
To comprehensively reveal molecular characterization of advanced CRC, we applied integrated proteomic and metabolomic analyses on serum samples from 20 patients with CRC at stage III or IV. Methods In the present study, we took advantage of nanoscale liquid chromatography and quadrupole time-of-flig...
ORGANISM(S): Homo Sapiens 
2021-03-29 | PXD025041 |
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