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ProteomicsA liquid chromatography-tandem mass spectrometry analysis of endogenous TWIST1 immunoprecipitates in the LSCs from MLL-AF9+ AML mice
We performed a liquid chromatography-tandem mass spectrometry analysis of endogenous TWIST1 immunoprecipitates in the LSCs isolated from MLL-AF9-driven AML mice
ORGANISM(S): Mus Musculus 
2022-10-09 | PXD037217 |
ProteomicsLysine-targeting, covalent inhibitors of bromodomain BD1 of BET proteins in live cells and animals
We report herein a set of activity-based probes (ABPs; P3-P7) based on various lysine-reactive covalent warheads capable of global profiling of ligandable lysine within BRDs in live cells and animals. Chemoproteomic experiments with P7 by utilizing 2-ethynylbenzaldehyde (EBA) identified 18 endogenou...
ORGANISM(S): Homo Sapiens Mus Musculus 
2025-04-10 | PXD058513 |
ProteomicsLC-MS/MS-based metabolomics and proteomics reveal the intervention of Kangnian Decoction on the postoperative intestinal adhesion of rats
This study aims to explore the therapeutic effects of KN decoction in a PIA rat model, as well as its potential mechanisms via metabolomics and proteomics analyses.
ORGANISM(S): Rattus Norvegicus 
2024-09-09 | PXD055723 |
ProteomicsAddressing Enzymatic-Independent Tumor-Promoting Function of NAMPT via two PROTAC-Mediated Degradation
The rate-limiting enzyme of salvage pathway for NAD+ synthesis, NAMPT, is aberrantly overexpressed in a variety of tumor cells and is a poor prognosis factor for patient survival. NAMPT plays a major role in tumor cell proliferation, acting concurrently as an NAD+ synthase and unexpectedly, an extra...
ORGANISM(S): Homo Sapiens 
2022-01-24 | PXD031185 |
ProteomicsAddressing Enzymatic-Independent Tumor-Promoting Function of NAMPT via PROTAC-Mediated Degradation
The rate-limiting enzyme of salvage pathway for NAD+ synthesis, NAMPT, is aberrantly overexpressed in a variety of tumor cells and is a poor prognosis factor for patient survival. NAMPT plays a major role in tumor cell proliferation, acting concurrently as a NAD+ synthase and unexpectedly, an extrac...
ORGANISM(S): Homo Sapiens 
2021-09-13 | PXD028453 |
ProteomicsChanges of Granulation Tissue Protein Mass Spectrometry in Foot Wound of Diabetes Mellitus after Negative Pressure wound therapy
Before and after negative pressure treatment in 3 diabetic foot patients, the granulation tissue of foot ulcer was sampled and analyzed quantitatively by LC-MS /MS method.
ORGANISM(S): Homo Sapiens 
2020-08-17 | PXD020929 |
ProteomicsThe outer membrane protein of Riemerella anatipestifer YM strain interacting with duck vitronectin was screened by pull-down assay sequencing by mass spectrometry and search for complement escape related protein of Riemerella anatipestifer YM strain.
Riemerella anatipestifer can cause infectious serositis in ducklings with high mortality. Vitronectin acts as a complement regulator and plays a role in the terminal pathway of complement activation. It is a widely used strategy for Gram-negative bacteria to capture vitronectin to the surface of bac...
ORGANISM(S): Riemerella Anatipestifer Ra-ym 
2023-02-01 | PXD039753 |
ProteomicsComprehensive analyses of the macrophages infected with avirulent and virulent Mycobacterium tuberculosis strains uncover distinct immune mechanisms and anti-TB effect of treated exosomes
Protein data of exosomes from Mycobacterium tuberculosis-infected macrophages
ORGANISM(S): Homo Sapiens 
2026-05-18 | PXD078478 |
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