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ProteomicsSynthetic biology meets proteomics: Construction of à la carte QconCATs for absolute protein quantification
We report a new approach to the assembly and construction of QconCATs, quantitative concatamers for proteomic applications that yield stoichiometric quantities of sets of stable isotope-labelled internal standards. The new approach is based on synthetic biology precepts of biobricks, making use of l...
ORGANISM(S): Escherichia Coli 
2022-07-18 | PXD027047 | panorama
ProteomicsDefective O-fucosylation of EDIL3 attenuates invasion and vascular remodeling of trophoblasts via LIFR signaling pathway in preeclampsia
Preeclampsia(PE)is a severe placental disorder that affects 3%-5% of all pregnancies worldwide. The primary cause of PE is abnormal placentationduring eanly pregnancy, including poor trophoblast invasion and insutficientapiral arteriole remodeling, Protein O-ucosylation is a type of protein posttran...
ORGANISM(S): Homo Sapiens 
2025-12-25 | PXD072416 |
ProteomicsIntegrated Proteomics and Metabolomics Link Acne to the Action Mechanisms of Cryptotanshinone Intervention
The label-free methods of proteomic combined with metabolomics were applied to explore the mechanisms of Cryptotanshinone intervention in rats with acne. These results propose action mechanisms for the use of CPT in acne, as a safe and potential new drug.
ORGANISM(S): Rattus Rattus 
2021-07-12 | PXD027219 |
ProteomicsTMT proteomics analysis of cerebrospinal fluid from patients with cerebral venous sinus thrombosis
In the present study, we detected the alterations of the CSF protein spectrum of CVST patients by TMT technique, screen differentially expressed proteins, analyze the functions of these signals through bioinformatics methods, and finally validate the key molecules through parallel reaction monitorin...
ORGANISM(S): Homo Sapiens 
2022-11-22 | PXD038259 |
ProteomicsMulberry leaf ameliorate STZ induced diabetic rat by regulating hepatic glycometabolism and fatty acid β-oxidation
Mulberry leaf ameliorate STZ induced diabetic rat by regulating hepatic glycometabolism and fatty acid β-oxidation
ORGANISM(S): Rattus Rattus 
2024-10-29 | PXD057279 |
ProteomicsProteomic stratification of prognosis and treatment options for small cell lung cancer
We analyzed surgically resected formalin-fixed, paraffin-embedded (FFPE) SCLC samples by proteomic profiling and stratified SCLC into three subtypes (S-I, S-II, and S-III) with distinct clinical outcomes and chemotherapy responses.
ORGANISM(S): Homo Sapiens 
PXD064316 |
ProteomicsDetection of betalains from the extracts of H. henanensis sp. nov.
Identification of betalains from the extracts of H. henanensis sp. nov. using untargeted metabolomics.
ORGANISM(S): Tardigrada 
2024-03-22 | PXD050882 |
ProteomicsProteomic analysis of Hypsibius henanensis sp.nov. suffered from 12C6+ heavy ion radiation based on label-free technology
Tardigrades are a kind of species that can tolerate ultra-high doses of ionizing radiation. Here, we used heavy ions at different doses of 0,200 and 2000Gy to irradiate Hypsibius henanensis sp.nov.. Label-free proteomic identification was performed on the samples, each dose containing 3 repetitions
ORGANISM(S): Tardigrada 
PXD045537 |
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