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MetabolomicsMetabolomic Responses of Guard Cells and Mesophyll Cells to Bicarbonate
Anthropogenic CO2 presently at 400 ppm is expected to reach 550 ppm in 2050, an increment expected to affect plant growth and productivity. Paired stomatal guard cells (GCs) are the gate-way for water, CO2, and pathogen, while mesophyll cells (MCs) represent the bulk cell-type of green leaves mainly...
2017-03-31 | MTBLS309 | MetaboLights
ProteomicsZSWIM4 regulates early embryonic patterning and BMP signaling pathway by promoting nuclear Smad1 degradation
The dorsoventral gradient of BMP signaling plays an essential role in embryonic patterning, with high BMP signal activating ventral-lateral mesoderm markers directly, and low BMP signal inducing neural tissues. The Zinc finger SWIM domain-containing protein 4 (zswim4) is expressed in the dorsal blas...
ORGANISM(S): Homo sapiens (Human) 
2024-05-22 | PXD035207 | Pride
Zswim4 Bmp Smad1 
Proteomics,Multiomicsembryo_proteome
We collected over 8000 mouse embryos of each developmental stage (zygote, 2-cell, 4-cell, 8-cell, morula, blastocyst) and performed tandem mass tag (TMT)-based quantitative mass spectrometry and identified nearly 5000 proteins for each stage. In-depth analysis indicates that protein expression profi...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2015-12-10 | MSV000079417 | MassIVE
ProteomicsCharacterization of indole-3-acetic acid biosynthesis and the effects of IAA exposure on the proteome of the plant-associated microbe Pantoea sp. YR343
Pantoea sp. YR343, isolated from the Populus deltoides rhizosphere, is a robust plant root colonizer that produces indole-3-acetic acid (IAA). Genomic and metabolomic analyses predicted that Pantoea sp. YR343 synthesizes IAA primarily using the indole-3-pyruvate pathway. Pantoea sp. YR343 proteomes...
ORGANISM(S): Pantoea Sp. Yr343 (ncbitaxon:1144341) 
2017-08-23 | MSV000081478 | MassIVE
MetabolomicsMulti-kingdom gut microbiota dysbiosis is associated with the development of pulmonary arterial hypertension

Gut microbiota dysbiosis has been implicated in pulmonary arterial hypertension (PAH). However, most studies have focused on the bacterial community and the exact role and mechanisms of multi-kingdom gut microbiota, including bacteria, archaea and fungi in PAH remains largely unclear. Idiopathic ...

2025-05-12 | MTBLS10563 | MetaboLights
UnknownZSWIM4 regulates embryonic patterning and BMP signaling by promoting nuclear Smad1 degradation.
Not available
S-EPMC10897318 | biostudies-literature
ProteomicsCross-link of Drosophila P75 dimer
Use XL-MS to detect whether dP75 can form homodimer
ORGANISM(S): Drosophila Melanogaster 
2024-12-12 | PXD058799 |
ProteomicsIntegrated proteomics and metabolomic analyses reveal the accumulation mechanism of bioactive components in Polygonatum odoratum
Polygonatum odoratum (MILL.) DRUCE is rich in bioactive components with high medicinal value. To maximize the clinical benefits, it is of great significance to efficiently extract key bioactive components from appropriate growth stages in which they are most abundant. In this study, we analyzed the ...
ORGANISM(S): Polygonatum Odoratum 
2024-12-14 | PXD058887 |
ProteomicsLongitudinal multi-omics analysis of convalescent individuals with respiratory sequelae 6–36 months after COVID-19
This study presents a longitudinal multi-omics analysis of COVID-19 convalescents with respiratory sequelae, spanning 6–36 months post-infection. The integrating proteomic and metabolomic profiling uncovers persistent molecular alterations, impaired diffusing capacity for carbon monoxide, and propos...
ORGANISM(S): Homo Sapiens 
2025-02-23 | PXD061113 |
UnknownMiR-30a Inhibits the Epithelial--Mesenchymal Transition of Podocytes through Downregulation of NFATc3.
Not available
S-EPMC4632736 | biostudies-literature
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