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TranscriptomicsFunctional Annotation of the Bovine Genome
The goal of the proposed project is to generate high-quality detailed transcript and chromatin status datasets from a comprehensive set of bovine tissues, developmental stages, and cells through a set of rationally selected assays. Experimental data generated by the project have been analyzed using ...
ORGANISM(S): Bos taurus 
2022-10-13 | E-MTAB-12052 | biostudies-arrayexpress
UnknownMapping and visualization of global research progress on deubiquitinases in ovarian cancer: a bibliometric analysis.
Not available
S-EPMC11424541 | biostudies-literature
Proteomicsm6A demethylase FTO stabilizes LINK-A to exert oncogenic roles via MCM3-mediated cell cycle progression and HIF-1α activation
To further delineate the downstream regulatory mechanism underlying the oncogenic roles of LINK-A, we performed mass spectrometry (MS) analyses to identify proteins precipitated with LINK-A in KYSE450 and YES2 cells. In total, 43 and 14 LINK-A-interacting proteins were identified in KYSE450 and YES2...
ORGANISM(S): Homo Sapiens 
PXD045414 |
ProteomicsComparative Proteomic AnalyComparative Proteomic Analysis of Aqueous Humor Reveals Biochemical Disparities in Eyes of High Myopic Patientssis of Aqueous Humor Reveals Biochemical Disparities in Eyes of High Myopic Patients
The pathogenesis of myopia involves different molecular mechanisms and pathways, which can be reflected in the aqueous humor. In our study, aqueous humor was collected for liquid chromatograph mass spectrometer (LC/MS) analysis from 30 individual eyes that underwent phacoemulsification and intraocul...
ORGANISM(S): Homo sapiens (Human) 
2024-05-23 | PXD047584 | Pride
Lipoprotein Myopia Proteomic analysis Aqueous humor Axial length 
ProteomicsProteomic of Stress-Induced Cardiomyopathy
Label free quantitative proteomics method was used to analyze protein abundance under defined conditions.
ORGANISM(S): Mus Musculus 
PXD056309 |
MetabolomicsImaginal disc growth factor maintains cuticle structure and controls melanization in the spot pattern formation of Bombyx mori

The complex stripes and patterns of insects play key roles in behavior and ecology. However, the fine-scale regulation mechanisms underlying pigment formation and morphological divergence remain largely unelucidated. Here we demonstrated that imaginal disc growth factor (IDGF) maintains cuticle s...

2020-09-20 | MTBLS1825 | MetaboLights
TranscriptomicsWhole transcriptome target sequencing: profiling gene expression and alternative polyadenylation with one pipeline.
We have developed a deep sequencing method called Whole Transcriptome Target Sequencing (WTTS), which sequences the 3’ ends of polyA+ RNA. This method can simultaneously profile gene expression and alternative polyadenylation. A pooled total RNA sample derived from three male and three female adul...
ORGANISM(S): Xenopus tropicalis 
2016-07-22 | E-GEOD-74919 | biostudies-arrayexpress
ProteomicsProteome of two developmental stages of Plukenetia volubilis seeds
To identify differentially abundant proteins (DAPs) at two developmental stages of P. volubilis seeds
ORGANISM(S): Plukenetia Volubilis 
PXD051626 |
ProteomicsPD-L1 Mediated Immune Evasion in Triple Negative Breast Cancer Is Linked to the Loss of ZNF652
The intrinsic regulation of PD-L1 expression remains unclear. Here we report that ZNF652 is a potent transcription repressor of PD-L1. ZNF652 frequently loses heterozygosity (LOH) in various cancers. Higher LOH rate and lack of estrogen-inducible transcription lead to suppressed expression of ZNF652...
ORGANISM(S): Homo Sapiens 
PXD045945 |
Proteomicsthe proteomics of IGFBP6 in endothelial cells (HUVECs)
To unravel the direct mechanism of the anti-inflammatory effects of IGFBP6 in ECs, we analysed HUVECs treated with either adenovirus-Flag-IGFBP6 (Ad-IGFBP6) or control adenovirus (Ad-NC). We precipitated IGFBP6 from overexpressed ECs followed by mass spectrometry.
ORGANISM(S): Homo Sapiens 
PXD052204 |
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