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Non-specific protective effects against reinfection have been described following infection with Candida albicans. Here we show that mice defective in functional T and B lymphocytes were protected against reinfection with C. albicans in a monocyte-dependent manner. C. albicans and beta glucans induc...
ORGANISM(S): Homo sapiens 
Total mRNA was isolated from parallel cultures of two Matalpha clones of each of the 7 temperature sensitive strains: STH1ts, SMC2ts, SMC3ts, STH1ts SMC2ts, STH1ts SMC3ts, SMC2ts SMC3ts, and STH1ts SMC2ts SMC3ts. The two biological replicates were processed in parallel and one was conjugated to Cy3,...
ORGANISM(S): Saccharomyces cerevisiae 
Monocyte differentiation into macrophages represents one of the cornerstone processes in innate host defense. In addition, immunological imprinting of either tolerance or trained immunity after an initial infection determines the functional fate of innate immune cells and the susceptibility of the h...
ORGANISM(S): Homo sapiens 
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