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TranscriptomicsCharacterization of the equine skeletal muscle transcriptome identifies novel functional responses to exercise training
Digital gene expression profiling was used to characterize the assembly of genes expressed in equine skeletal muscle and to identify the subset of genes that were differentially expressed following a ten month period of exercise training. The study cohort comprised 7 thoroughbred racehorses from a s...
ORGANISM(S): Equus caballus 
2010-04-09 | E-GEOD-21269 | biostudies-arrayexpress
TranscriptomicsRNA-seq profiling of the bovine cervix at 6 timepoints during the peri-oestrus period.
The estrous cycles of Limousin heifers (n = 30) were synchronized by insertion of a controlled internal drug release (CIDR) device (1.94 g progesterone; Pfizer Animal Health) placed into the vagina for 8 days. A 0.5 mg intramuscular injection of a prostaglandin F2α (PG) analogue (PG, Estrumate, Sher...
ORGANISM(S): Bos taurus 
2013-01-04 | E-GEOD-38225 | biostudies-arrayexpress
TranscriptomicsA differential polarization of Th1, Th2 and Treg immune response determines resistance and susceptibility of sheep breeds to Teladorsagia circumcincta infection
Gastrointestinal nematode (GIN) is a major economic and health concern is sheep farming. Sheep breeds such as Texel are relatively resistant to GIN than the Suffolk. With the objective to understand the underlying genetic mechanism of resistance and susceptibility at the transcriptomic level, two gr...
ORGANISM(S): Ovis aries 
2014-01-01 | E-GEOD-43241 | biostudies-arrayexpress
TranscriptomicsWhole-transcriptome, high-throughput RNA sequence analysis of the bovine macrophage response to MycobacteriumM-BM- bovis infection in vitro
Background: MycobacteriumM-BM- bovis, the causative agent of bovine tuberculosis, is an intracellular pathogen that can persist inside host macrophages during infection via a diverse range of mechanisms that subvert the host immune response. In the current study, we have analysed and compared the tr...
ORGANISM(S): Bos taurus 
2013-03-26 | E-GEOD-45439 | biostudies-arrayexpress
TranscriptomicsAn integrated approach combining RNA-seq, Ribo-seq and Proteomics identifies the coding potential of Mycobacterium abscessus
The objective of this study is to develop an integrated map for the M. abscessus ATCC19977 organism. Among the data types contributing to the development of this map are next-generation RNA-sequencing, differential RNA-sequencing, ribosome profiling, and mass spectrometry. The design of the study co...
ORGANISM(S): Mycobacterium abscessus ATCC 19977 
2016-03-30 | E-GEOD-72996 | biostudies-arrayexpress
GenomicStudy of Irish Amyotrophic Lateral Sclerosis (SIALS)

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by loss of motor neurons. Epidemiological studies indicate that 2-5% of cases are familial, usually with an autosomal dominant pattern of inheritance. For a portion of these, causative genes have been...

phs000127 | dbGaP
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