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ProteomicsA Sensitive and Controlled Data-Independent Acquisition Method for Proteomic Analysis of Cell Therapies
Mass Spectrometry (MS)-based proteomic measurements are uniquely poised to impact the development of cell and gene therapies. With the adoption of rigorous instrumental performance controls (PQs), large-scale proteomics can move from a research to a manufacturing control tool. Especially suited, dat...
ORGANISM(S): Homo sapiens (Human) 
2022-04-11 | PXD029780 | Pride
Car-t cells Performance control Data-independent acquisition Swath acquisition Jurkat cells Proteomics 
ProteomicsLabel-free Quantification of Proteins in Single Embryonic Cells with Neural Fate in the Cleavage-Stage Frog (Xenopus laevis) Embryo using CE-ESI-HRMS
In this work, we integrate capillary electrophoresis electrospray ionization mass spectrometry, bottom-up proteomics, and single-cell microanalysis to enable the label-free quantification (LFQ) of proteins in single embryonic cells (D11 blastomeres) in the 16-cell frog (Xenopus laevis) embryo. Based...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2016-06-23 | PXD004174 | Pride
Blastomere Embryo Proteomics Xenopus Mass spectrometry Fusion Label free quantification Single cell Lfq Capillary electrophoresis Electrospray ionization Impact hd 
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