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TranscriptomicsPAO1-Lon-ciprofloxacin
Microarray experiments were preformed comparing the effect of sub-inhibitory concentrations of ciprofloxacin on five independent cultures of PAO1 and the PAO1 Lon mutant
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2012-03-25 | E-MTAB-1000 | biostudies-arrayexpress
TranscriptomicslonB mutant
The bacterial Lon protease participates in a variety of biological processes. In Pseudomonas syringae, mutation of lon is known to activate hrpL and a few hrpL-regulated genes in the rich medium. The elevated expression of hrpL and hrpL-regulated genes results from of increased stability of HrpR, th...
ORGANISM(S): Pseudomonas syringae pv. tomato str. DC3000 
2007-10-14 | E-GEOD-6121 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Lon and FtsH conditional mutants of Mycoplasma pneumoniae under depleting and inducing conditions
Using Mycoplasma pneumoniae as a model organism, we conditionally depleted the two essential ATP-dependent proteases (Lon and FtsH) of this bacterium, by engineering three strains carrying a Lon and/or FtsH inducible expression locus. An integrative comparative study combining label-free shotgun pro...
ORGANISM(S): Mycoplasma pneumoniae M129 
2020-11-10 | E-MTAB-8537 | biostudies-arrayexpress
ProteomicsIdentification of substrates of LarA-activated Lon protease and Identification of Lon protease interactome
With this analysis we aim to identify proteins that are substrates of LarA-activated Lon protease in Caulobacter crescentus. We will compare samples of wild type cells either harboring an empty vector (vector control, VC) or overexpressing 3xFLAG-tagged LarA (F-LarA). Based on our previous data we h...
ORGANISM(S): Caulobacter crescentus (strain NA1000 / CB15N) 
2023-10-25 | PXD036514 | Pride
Caulobacter crescentus Lon activity regulator Lara Lon protease 
ProteomicsIdentifying putative substrates of Lon protease in Pseudomonas aeruginosa
We aim to identify potential substrates of the Lon protease in P. aeruginosa. Samples with the lon protease overexpressed or deleted were compared to the wild type to observe the proteins whose steady-state levels changed with change in Lon levels. We used spectinomycin to inhibit protein synthesis ...
ORGANISM(S): Bacteria Pseudomonas aeruginosa PA1 
2025-06-13 | PXD063095 | Pride
Proteomics Lon protease Bacteria Pseudomonas aeruginosa Substrates 
GenomicsRNA-seq and ChIP-seq for Lon
RNA-seq and ChIP-seq for Lon
PRJNA564989 | ENA
TranscriptomicsTranscription profiling of wild type and lon knock-out E. coli in M9 media at log phase
Lon- versus Lon+ in M9 0,1%glucose log phase
ORGANISM(S): Escherichia coli 
2008-06-10 | E-MEXP-1484 | biostudies-arrayexpress
GenomicsChip-seq analysis of hrpRSL and Lon in Pseudomonas syringas
Pseudomonas syringae uses HrpRSL to regulate the expression of type III secretion system (T3SS) genes and bacterial virulence. However, the molecular mechanism and the regulons of HrpRSL have yet to be fully elucidated. Here, we performed chromatin immunoprecipitation followed by high-throughput DNA...
ORGANISM(S): Pseudomonas syringae 
2015-12-31 | E-GEOD-65437 | biostudies-arrayexpress
TranscriptomicsVibrio cholerae lon protease mutant microarray analysis
Lon protease is known to regulate various transcriptional regulators in other bacterial organisms. To understand whether lon protease is involved in transcriptional changes in Vibrio cholerae, wholel-genome level transcriptional profiling was performed using custom microarrays. Transcriptomes of lon...
ORGANISM(S): Vibrio cholerae 
2016-01-06 | E-GEOD-73023 | biostudies-arrayexpress
GenomicsThe Lon protease links nucleotide metabolism with proteotoxic stress
The Lon protease links nucleotide metabolism with proteotoxic stress
PRJNA639285 | ENA
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