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GenomicsRNA polymerase V targets transcriptional silencing components to promoters of protein-coding genes
Transcriptional gene silencing controls transposons and other repetitive elements through RNA-directed DNA methylation (RdDM) and heterochromatin formation. A key component of the Arabidopsis RdDM pathway is ARGONAUTE4 (AGO4), which associates with sizs to mediate DNA methylation. Here, we show that...
ORGANISM(S): Arabidopsis thaliana 
2012-10-17 | E-GEOD-35381 | biostudies-arrayexpress
TranscriptomicsRNA at 92 M-BM-0C: the non-coding transcriptome of the hyperthermophilic archaeon Pyrococcus abyssi.
The non-coding transcriptome of the hyperthermophilic archaeon Pyrococcus abyssi is investigated using the RNA-seq technology. A dedicated computational pipeline analyzes RNA-seq reads and prior genome annotation to identify small RNAs, untranslated regions of mRNAs, and cis-encoded antisense transc...
ORGANISM(S): Pyrococcus abyssi 
2014-05-31 | E-GEOD-58131 | biostudies-arrayexpress
TranscriptomicsSequencing of the non-ribosomal transcriptome allows the simultaneous identification of protein-coding and non-protein-coding RNAs
Deep Sequencing of protein-coding and non-protein-coding RNAs from mouse differentiated embryonic stem cells and 14.5dpc mouse fetal head Analysis of Ribominus RNA from mouse differentiated embryonic stem cells and 14.5dpc mouse fetal head There are no processed data files for GSM566806-GSM566811. ...
ORGANISM(S): Mus musculus 
2011-12-06 | E-GEOD-22959 | biostudies-arrayexpress
GenomicsCustom long non-coding RNA capture enhances detection sensitivity in different human sample types.
Long non-coding RNAs (lncRNAs) are a heterogeneous group of transcripts that lack protein coding potential and display regulatory functions in various cellular processes. As a result of their cell- and cancer-specific expression patterns, lncRNAs have emerged as potential diagnostic and therapeutic ...
EGAS00001005418 | EGA
ProteomicsProtein interaction partners of long non-coding RNA NUDT6 in human aortic smooth muscle cells
The long non-coding RNA NUDT6 was found to be deregulated in abdominal aortic aneurysm (AAA) with higher expression in diseased human tissue specimens versus control aortic tissue. Apart from the already well-studied DNA: RNA interaction as a natural antisense transcript to Fibroblast Growth Factor ...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD033922 | Pride
Abdominal aortic aneurysm Vascular disease Long non-coding rnas Lc-msms Rna/protein interaction 
TranscriptomicsControl of Somatic Tissue Differentiation by the Long Non-Coding RNA TINCR (HTS)
Several of the thousands of human long non-coding RNAs (lncRNAs) have been functionally characterized; however, potential roles for lncRNAs in somatic tissue differentiation remain poorly understood. Here we show that a 3.7kb lncRNA, terminal differentiation-induced ncRNA (TINCR), controls human epi...
ORGANISM(S): Homo sapiens 
2012-10-10 | E-GEOD-40121 | biostudies-arrayexpress
ProteomicsA novel protein coding potential of long intergenic non-coding RNAs (lincRNAs) in the kinetoplastid protozoan parasite Leishmania major
Leishmania major is a kinetoplastid protozoan parasite which causes the debilitating infectious disease cutaneous leishmaniasis (CL). This disease results in scars and disfiguration of the infected individuals. The L. major genome was the first leishmanial genome to be sequenced in 2005 and this stu...
ORGANISM(S): Leishmania major 
2016-05-11 | PXD002465 | Pride
Cutaneous leishmaniasis Proteomics Gene annotations Non-coding rna Protozoan parasite 
TranscriptomicsLong non-coding RNA expression profiling in the NCI60 cancer cell line panel using high-throughput RT-qPCR
Long non-coding RNAs (lncRNAs) form a new class of RNA molecules implicated in various aspects of protein coding gene expression regulation. To study lncRNAs in cancer, we generated expression profiles for 1708 human lncRNAs in the NCI60 cancer cell line panel using a high-throughput nanowell RT-qPC...
ORGANISM(S): Homo sapiens 
2016-06-29 | E-GEOD-80332 | biostudies-arrayexpress
ProteomicsCRISPR-assisted RNA-protein interaction detection (CARPID) combined with quantitative mass spectrometry was used to identify proteins interacting with the long non-coding RNA (lncRNA) Taurine Up-regulated 1 (TUG1) in HEK293T cells under physiological conditions and after Camptothecin (CPT) treatment.
This project utilized CRISPR-assisted RNA-protein interaction detection (CARPID) combined with mass spectrometry to identify proteins interacting with the long non-coding RNA (lncRNA) TUG1 in HEK293T cells. TUG1 preferentially interacts with known R-loop-associated proteins, particularly under Campt...
ORGANISM(S): Homo Sapiens (human) 
2025-07-17 | PXD049137 | JPOST Repository
ProteomicsInteractome of the long non-protein coding RNA (lncRNA) D4Z4 binding element-transcript (DBE-T)
Facioscapulohumeral muscular dystrophy (FSHD) is an inherited progressive neuromuscular disorder that afflicts both children and adults regardless of gender. FSHD is caused by aberrant gain of expression of the transcription factor DUX4, which triggers a pro-apoptotic transcriptional program leading...
ORGANISM(S): Homo sapiens (Human) 
2023-04-11 | PXD036038 | Pride
Facioscapulohumeral muscular dystrophy (fshd) Long non-protein coding rna Affinity proteomics 
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