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MetabolomicsGut microecology of long COVID persisting for 2 years

Long COVID is an emerging global public health issue. The human gut microbiota (GM) has been identified as a potentially important factor influencing the development of long COVID. This study aims to understand the prevalence, risk factors and GM of long COVID persisting for 2 years in Hainan Pro...

2025-03-26 | MTBLS11718 | MetaboLights
MetabolomicsSequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID

The post-acute sequelae of COVID-19 (PASC), also known as long COVID, is often associated with debilitating symptoms and adverse multisystem consequences. We obtain plasma samples from 117 individuals during and 6 mth following their acute phase of infection to comprehensively profile and as...

2024-02-23 | MTBLS7337 | MetaboLights
TranscriptomicsSpatial Transcriptomics of the Epipharynx in Long COVID: Exploring SARS-CoV-2 Signalling Pathways and the Therapeutic Potential of Epipharyngeal Abrasive Therapy
10X VisiumHD spatial transcriptomics of epipharynx from three patients with long COVID and two control individuals without COVID-19.
ORGANISM(S): Homo sapiens 
2025-02-24 | E-MTAB-14669 | biostudies-arrayexpress
ProteomicsImmune cell proteomes of Long COVID patients have functional changes similar to those in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.
To investigate the pathophysiology of Long COVID (LC), a pilot study of patients and healthy controls has used quantitative proteomics to discover changes in peripheral blood mononuclear cell (PBMC) proteoms. The proteomes of LC patients and healthy controls were analysed by Sequential Window Acquis...
ORGANISM(S): Homo sapiens (Human) 
2025-08-05 | PXD045508 | Pride
Me/cfs Swath-ms Long covid 
Proteomics‘The long tail of Covid 19’ - The detection of a prolonged inflammatory response after a SARS-CoV-2 infection in asymptomatic and mildly affected patients
‘Long Covid’ or medical complications associated with a post SARS Covid 2 infection, are a significant post-viral complication that is being more and more commonly reported in patients. Therefore, there is an increasing need to understand the disease mechanisms, identify drug targets and inflammato...
ORGANISM(S): Homo Sapiens 
2021-01-21 | PXD022159 | panorama
ProteomicsMulti-omics provide evidence for an anti-inflammatory immune signature and metabolic alterations in patients with Long COVID Syndrome – an exploratory study (plasma)
Despite the increasing prevalence of patients with Long Covid Syndrome (LCS), to date the pathophysiology of the disease is still unclear, and therefore diagnosis and therapy are a complex effort without any standardization. To address these issues, we performed a broad exploratory screening study a...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD036969 | Pride
Long covid syndrome  chronic fatigue syndrome  proteomics  metabolomics  macrophage polarization 
ProteomicsPulmonary and Renal Long COVID at Two-year Revisit
To outline the temporal changes of long COVID, we profiled serum proteomes (dataset SP2) and urine proteomes (dataset UP2). The SP2 were measured for 37 patients during the disease (T1), the convalescence (T2), and at the 1-year revisit (T3); the UP2 were measured for 28 patients during the disease ...
ORGANISM(S): Homo Sapiens 
PXD027557 |
ProteomicsHuman serum LC-MS/MS for long-term persistent COVID-19 patients
The emergence of a new type of COVID-19 patients, who were retested positive after hospital discharge with long-term persistent SARS-CoV-2 infection but without COVID-19 clinical symptoms (hereinafter, LTPPs), poses novel challenges to COVID-19 treatment and prevention. Why was there such a contradi...
ORGANISM(S): Homo sapiens (Human) 
2022-10-22 | PXD036609 | Pride
Human Dia Serum Covid-19 Lc-ms/ms 
GenomicsLong COVID
Nasal Microbiota and Clinical Features in Acute Flu-Like Illness: COVID-19 Status and Long COVID Follow-Up
PRJEB102306 | ENA
ProteomicsMolecular Insights into Long COVID: Plasma Proteomics Reveals Oxidative Stress, Coagulation Cascade Activation, and Glycolytic Imbalance
Persistent symptoms following SARS-CoV-2 infection are the hallmark of post-COVID condition (PCC), also referred to as long COVID. However, our knowledge is limited on the underlying molecular mechanisms. In this study, we performed data-independent acquisition mass spectrometry plasma proteomics (D...
ORGANISM(S): Homo sapiens (Human) 
2026-03-24 | PXD066724 | Pride
Long covid  post covid-19 condition  oxidative stress  glutathione  plasma proteomics 
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