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ProteomicsCharting the Circulating Proteome in ME/CFS Using Cross System Profiling to Uncover Mechanistic Insights
This dataset contains processed aptamer-based serum proteomics data from ME/CFS patients and healthy controls, analyzed using the 7k SomaScan assay (v4.1) platform. It includes log2-transformed intensities for 7326 aptamers (6494 protein targets), cohort metadata (age range, sex, BMI category, fasti...
ORGANISM(S): Homo sapiens (Human) 
2026-01-21 | PAD000026 | Pride
Serum Me/cfs 
ProteomicsProteomic Signatures in Cerebrospinal Fluid and Their Clinical Associations in Patients with ME/CFS
This study evaluated the cerebrospinal fluid (CSF) proteomes from 31 patients diagnosed with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). We quantified 902 proteins, each expressed in at least eleven samples, and systematically categorized clinical factors relevant to ME/CFS symptoms...
ORGANISM(S): Homo sapiens (Human) 
2026-04-06 | PXD076216 | Pride
Cerebrospinal fluid Myalgic encephalomyelitis Chronic fatigue syndrome Proteomics Me/cfs Lc-ms/ms 
UnknownEpigenetic modifications and glucocorticoid sensitivity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).
Not available
S-EPMC5324230 | biostudies-literature
ProteomicsPassive transfer of IgG immune complex from ME/CFS patients alters mitochondrial architecture and function
Autoimmunity is an established clinical feature in both Myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) and Post-Acute Sequelae of COVID (PASC). Passive transfer of immunoglobulins from patients' sera into mice induces some clinical features of PASC. IgG-induced transfer of disease phe...
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD065439 | Pride
Serum igg proteomics Me/cfs Ms 
ProteomicsProteomic Analysis of Cerebrospinal Fluids from Chronic Fatigue Syndrome Patients with and without Co-existing Fibromyalgia
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and fibromyalgia have overlapping neurologic symptoms particularly disabling fatigue. This has given rise to the question whether they are distinct central nervous system (CNS) entities or is one an extension of the other. To investigate th...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-11-09 | MSV000090685 | MassIVE
UnknownA Comprehensive Examination of Severely Ill ME/CFS Patients.
Not available
S-EPMC8535418 | biostudies-literature
UnknownCentral 5-HTergic hyperactivity induces myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS)-like pathophysiology.
Not available
S-EPMC10773012 | biostudies-literature
GenomicsME/CFS plasma metagenomics
Metagenomics does not detect differences in microbial DNA content in the plasma of ME/CFS patients compared to controls
PRJEB14374 | ENA
GenomicsImmune Exhaustion in ME/CFS and long COVID
Immune Exhaustion in ME/CFS and long COVID
PRJNA1150265 | ENA
UnknownHuman Leukocyte Antigen alleles associated with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).
Not available
S-EPMC7093502 | biostudies-literature
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