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UnknownGenetic Predictors of Depressive Symptoms in the Look AHEAD Trial.
Not available
S-EPMC4643359 | biostudies-literature
TranscriptomicsTranscription profiling of mouse LckCre, CD4Cre-Ctnnbex3 mutants before and after T-cell transformation reveals stabilization of b-catenin induces lymphomas
Activation of b-catenin has been causatively linked to the etiology of colon cancer. Conditional stabilization of this molecule in pro-T-cells promotes thymocyte development without the requirement for preTCR signaling. We show here that activated b-catenin stalls the developmental transition from t...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7050 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human T-ALL cell cultures treated with Compound E, a gamma-secretase inhibitor or vehicle only (DMSO) for 24 h
The NOTCH1 signaling pathway directly links extracellular signals with transcriptional responses in the cell nucleus and plays a critical role during T-cell development and in the pathogenesis over 50% of human T-cell lymphoblastic leukemia (T-ALL) cases. However, little is known about the transcrip...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-5827 | biostudies-arrayexpress
UnknownObesity susceptibility loci and dietary intake in the Look AHEAD Trial.
Not available
S-EPMC3349457 | biostudies-literature
UnknownIntegrative network analysis reveals USP7 haploinsufficiency inhibits E-protein activity in pediatric T-lineage acute lymphoblastic leukemia (T-ALL).
Not available
S-EPMC7933146 | biostudies-literature
UnknownWeight Change During the Postintervention Follow-up of Look AHEAD.
Not available
S-EPMC9277114 | biostudies-literature
UnknownFactors influencing enrollment of African Americans in the Look AHEAD trial.
Not available
S-EPMC3843916 | biostudies-literature
ProteomicsPaenarthrobacter ilicis 6C glucose vs xanthan proteome
A novel Paenarthrobacter ilicis 6C isolate from soil found in Bielefeld, Germany, was sequenced and characterized by proteome analysis to provide the first clear look at a novel genus in the realm of xanthan degrading microorganisms. This research provides additional groundwork for the ongoing chara...
ORGANISM(S): Paenarthrobacter ilicis 
2025-06-13 | PXD063987 | Pride
Paenarthrobacter Proteomics Xanthan degradation Glucose metabolism Proteome 
TranscriptomicsGene expression profile of mouse breast cancer V720 cells treated with vehicle or PD 0332991
D-cyclins represent components of cell cycle machinery. To test the efficacy of targeting D-cyclins in cancer treatment, we engineered mouse strains which allow acute and global ablation of individual D-cyclins in a living animal. Ubiquitous shutdown of cyclin D1 or inhibition of cyclin D associated...
ORGANISM(S): Mus musculus 
2012-10-16 | E-GEOD-40513 | biostudies-arrayexpress
TranscriptomicsGene expression profile of human T-ALL cell line KOPTK1 treated with vehicle or PD 0332991
D-cyclins represent components of cell cycle machinery. To test the efficacy of targeting D-cyclins in cancer treatment, we engineered mouse strains which allow acute and global ablation of individual D-cyclins in a living animal. Ubiquitous shutdown of cyclin D1 or inhibition of cyclin D associated...
ORGANISM(S): Homo sapiens 
2012-10-16 | E-GEOD-40512 | biostudies-arrayexpress
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