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MetabolomicsATAD3A has a scaffolding role regulating mitochondria inner membrane structure and protein assembly

The ATPase Family AAA Domain Containing 3A (ATAD3A), is a mitochondrial inner membrane protein conserved in metazoans. ATAD3A has been associated with several mitochondrial functions, including nucleoid organization, cholesterol metabolism, and mitochondrial translation. To address its primary ro...

2022-01-14 | MTBLS3786 | MetaboLights
GenomicsLoop Assembly
Loop Assembly: library of plasmids
PRJEB29863 | ENA
ProteomicsA boundary-defining protein facilitates megabase-scale regulatory chromosomal loop formation in Drosophila neurons
Meta-loops are large chromosomal loops that connect specific neuronal genes with non-coding DNA elements, enabling megabase-range regulation of gene transcription in fly neurons. To reveal how highly specific meta-loop interactions form, we developed an unbiased approach to identify proteins from Dr...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2025-04-11 | PXD060311 | Pride
Meta-loop Neuron 3d genome organization Cp190 Drosophila Transcription factor Lola 
TranscriptomicsArgonaute Surveillance and Dicer-Independent priRNAs TriggerRNAi and Heterochromatin Formation
The assembly of fission yeast pericentromeric heterochromatin and generation of small interfering RNAs (siRNAs) from noncoding centromeric transcripts are mutually dependent processes. How this interdependent positive feedback loop is first triggered is a fundamental unanswered question. Here we sho...
ORGANISM(S): Schizosaccharomyces pombe 
2010-02-23 | E-GEOD-19734 | biostudies-arrayexpress
TranscriptomicsA basic helix-loop-helix transcription factors network mediates the brassinosteroid signal [RNA-seq]
To understand how atypical bHLH, INCREASED LEAF INCLINATION1 (ILI1)-BINDING bHLH-1 (IBH1) (At2g43060), and close homologue, IBH1-like1 (IBL1) (At4g30410), interact to regulate cell elongation, genome-wide RNA-Seq expression analyses of IBH1 and IBL1 gain-(IBH1OE, IBL1OE) and loss-of-function (ibh1 (...
ORGANISM(S): Arabidopsis thaliana 
2014-03-05 | E-GEOD-51119 | biostudies-arrayexpress
GenomicsRNA transcripts regulate G-quadruplex landscapes through G-loop formation (G4 and R-loop CUT&Tag)
RNA transcripts regulate G-quadruplex landscapes through G-loop formation (G4 and R-loop CUT&Tag)
PRJNA1120075 | ENA
UnknownUniversal loop assembly: open, efficient and cross-kingdom DNA fabrication.
Not available
S-EPMC7052795 | biostudies-literature
ProteomicsThe assembly of the Mitochondrial Complex I Assembly complex uncovers a redox pathway coordination
The Mitochondrial Complex I Assembly (MCIA) complex is essential for the biogenesis of respiratory Complex I (CI), the first enzyme in the respiratory chain, which has been linked to Alzheimer’s disease (AD) pathogenesis. However, how MCIA facilitates CI assembly, and how it is linked with AD pathog...
ORGANISM(S): Homo sapiens (Human) Escherichia coli 
2023-12-13 | PXD042905 | Pride
Keywords: oxidative phosphorylation (oxphos) Mitochondrial complex i assembly complex (mcia) Fatty acid oxidation (fao) Amyloid-β Ecsit phosphorylation Cryo-em 
GenomicsA basic helix-loop-helix transcription factors network mediates the brassinosteroid signal [ChIP-seq]
To investigate the genome-wide occupancies of INCREASED LEAF INCLINATION1 (ILI1)-BINDING bHLH-1 (IBH1) (At2g43060), IBH1 ChIP analysis followed by direct sequencing (ChIP-Seq) on the p35S::IBH1-GFP (IBH1OE) line and a control line p35S::GFP (GFP OE) were conducted. Antibodies against GFP in the GFP...
ORGANISM(S): Arabidopsis thaliana 
2014-03-05 | E-GEOD-51120 | biostudies-arrayexpress
UnknownFork pausing allows centromere DNA loop formation and kinetochore assembly.
Not available
S-EPMC6243264 | biostudies-literature
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