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ProteomicsA boundary-defining protein facilitates megabase-scale regulatory chromosomal loop formation in Drosophila neurons
Meta-loops are large chromosomal loops that connect specific neuronal genes with non-coding DNA elements, enabling megabase-range regulation of gene transcription in fly neurons. To reveal how highly specific meta-loop interactions form, we developed an unbiased approach to identify proteins from Dr...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2025-04-11 | PXD060311 | Pride
Meta-loop Neuron 3d genome organization Cp190 Drosophila Transcription factor Lola 
UnknownHubs and interaction: the brain's meta-loop.
Not available
S-EPMC11903256 | biostudies-literature
UnknownEfficacy and safety of combining a thiazide diuretic with a loop diuretic in decompensated heart failure: A systematic review and meta-analysis.
Not available
S-EPMC12301972 | biostudies-literature
UnknownLoop diuretics in adult intensive care patients with fluid overload: a systematic review of randomised clinical trials with meta-analysis and trial sequential analysis.
Not available
S-EPMC9192894 | biostudies-literature
UnknownGhost Ileostomy Versus Loop Ileostomy Following Oncologic Resection for Rectal Cancer: A Systematic Review and Meta-Analysis.
Not available
S-EPMC10403968 | biostudies-literature
UnknownValue of implantable loop recorders in detecting atrial fibrillation for stroke prevention: a systematic review and meta-analysis.
Not available
S-EPMC12519339 | biostudies-literature
UnknownBetter TIR, HbA1c, and less hypoglycemia in closed-loop insulin system in patients with type 1 diabetes: a meta-analysis.
Not available
S-EPMC9024214 | biostudies-literature
UnknownDiagnosis of visceral and cutaneous leishmaniasis using loop-mediated isothermal amplification (LAMP) protocols: a systematic review and meta-analysis.
Not available
S-EPMC8785018 | biostudies-literature
TranscriptomicsChromosome-level organization of the regulatory genome in the Drosophila nervous system [scRNA-seq]
We present evidence for a new level of genome folding, whereby distant domains megabases apart fuse to form meta-domains. Within meta-domains, certain gene promoters pair with structural intergenic elements in the distant TAD. These long-range associations occur in a large fraction of Drosophila neu...
ORGANISM(S): Drosophila melanogaster 
2023-08-01 | GSE214706 | GEO
UnknownThe impact of closed-loop automated insulin delivery systems on hypoglycaemia awareness in people living with type 1 diabetes: A systematic review and meta-analysis.
Not available
S-EPMC11599659 | biostudies-literature
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