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Laser Microdissection (LMD) associated to LC-MS/MS were used to analyze the proteome of neoplastic islands and stroma tumor of Formalin-Fixed and Paraffin Embedded (FFPE) OSCC tissues to identify proteins of prognostic value. Label-free protein quantification and statistical analysis revealed neopla...
ORGANISM(S): Homo sapiens (Human) 
2018-09-10 | PXD007232 | Pride
Proteomics of serum extracellular vesicles identify the severity of COVID-19
ORGANISM(S): Homo sapiens (Human) 
2026-02-05 | PXD041947 | Pride
Protease activity has been associated with pathological processes that can lead to cancer development and progression. However, understanding the pathological unbalance in proteolysis is challenging since changes can occur simultaneously at protease, their inhibitor and substrate levels. Here, we pr...
ORGANISM(S): Homo sapiens (Human) 
2020-11-13 | PXD020111 | Pride
Considering that these potential diagnostic and prognostic targets may be regulated by events that do not imply variation in protein abundance levels, we investigated the hypothesis that changes in protein conformation can be associated with diagnosis and prognosis, revealing biological processes an...
ORGANISM(S): Homo sapiens (Human) 
2025-03-11 | PXD042574 | Pride
The relationship between the microbial changes with clinical-pathological outcomes are still far from being conclusive. Herein, we investigate the ability of metagenomics (MG) and metaproteomics (MP) saliva data in distinguishing C, L0 and L1 patients. For that, we combined two strategies using MG a...
ORGANISM(S): Homo sapiens (Human) 
2022-11-09 | PXD022859 | Pride
Protease activity has been associated with pathological processes that can lead to cancer development and progression. However, understanding the pathological unbalance in proteolysis is challenging since changes can occur simultaneously at protease, their inhibitor and substrate levels. In this wor...
ORGANISM(S): Homo sapiens (Human) 
2020-11-13 | PXD020211 | Pride
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