Sort   by:  
 Page size 
ProteomicsLOPIT-DC subcellular map of U-2 OS cells
Generation of a high-resolution subcellular localisation map for the proteome of the human cancer cell line U-2 OS, using the newly developed LOPIT-DC method. Comparison of the results generated using LOPIT-DC with data generated using the well-established hyperLOPIT method and data mining regarding...
ORGANISM(S): Homo sapiens (Human) 
2019-01-23 | PXD011254 | Pride
Lopit-dc Hyperlopit Cancer subcellular map Spatial proteomics 
UnknownCombining LOPIT with differential ultracentrifugation for high-resolution spatial proteomics.
Not available
S-EPMC6338729 | biostudies-literature
ProteomicsLOPIT-DC subcellular map of U-2 OS cells
Generation of a high-resolution subcellular localisation map for the proteome of the human cancer cell line U-2 OS, using the newly developed LOPIT-DC method. Comparison of the results generated using LOPIT-DC with data generated using the well-established hyperLOPIT method and data mining regarding...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-11-23 | MSV000088434 | MassIVE
ProteomicsTHE PHARMACOLOGICAL RESCUE OF CFTR BY LUMACAFTOR (VX-809) IN THE CYSTIC FIBROSIS BRONCHIAL EPITHELIUM IS ASSOCIATED WITH AN EXTENSIVE REORGANIZATION OF MITOCHONDRIA.
Cystic Fibrosis (CF) is a genetic disorder CF is caused by mutations of the gene encoding for the cystic fibrosis transmembrane conductance regulator protein (CFTR), a transmembrane anion channel expressed at the apical membrane of several organs, including the epithelial cells of the airway. CFTR m...
ORGANISM(S): Homo sapiens (Human) 
2022-08-11 | PXD028393 | Pride
Lopit-dc Spatial proteomics Vx-809 Cfbe41o- cells Cystic fibrosis 
ProteomicsOperation of a TCA cycle subnetwork in the mammalian nucleus
Nucleic acid and histone modifications critically depend on central metabolism for substrates and co-factors. Although a few enzymes related to the formation of these required metabolites have been reported in the nucleus, the corresponding metabolic pathways are considered to function elsewhere in ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD032918 | Pride
Succinylation Subcellular localisation Lopit Spatial proteomics 
ProteomicsReduced mitochondria provide an essential function for the cytosolic methionine cycle
Since the discovery of eukaryotes without mitochondria, intestinal flagellates oxymonads, it was clear that the loss of mitochondria was facilitated by the remodelling of the FeS cluster synthesis. Yet, this remodelling is common for a broader linage including free-living species with reduced mitoch...
ORGANISM(S): Paratrimastix pyriformis 
2023-03-11 | PXD033021 | Pride
Reduced mitochondria Glycine cleavage system Paratrimastix Mitochondrial loss Lopit One-carbon metabolism Proteome Methionine cycle 
UnknownPattern Analysis of Organellar Maps for Interpretation of Proteomic Data.
Not available
S-EPMC9149908 | biostudies-literature
ProteomicsSimultaneous characterisation of RNA and protein subcellular dynamics
Existing methods to analyse RNA localisation are constrained to specific RNAs or subcellular niches, precluding the cell-wide mapping of RNA. We present Localisation of RNA (LoRNA), which maps, at once, RNAs to membranous (nucleus, ER and mitochondria) and membraneless compartments (cytosol, nucleol...
ORGANISM(S): Homo sapiens (Human) 
2022-01-25 | PXD030456 | Pride
Dynamics Subcellular localisation Tmt Spatial-proteome Lopit 
ProteomicsSpatial proteomics defines the content of trafficking vesicles captured by golgin tethers
Intracellular traffic between compartments of the secretory and endocytic pathways is mediated by vesicle-based carriers. The proteomes of carriers destined for many organelles are ill-defined because the vesicular intermediates are transient, low-abundance and difficult to purify. Here, we combine ...
ORGANISM(S): Homo sapiens (Human) 
2020-12-01 | PXD018110 | Pride
Lopit-dc Organell protein relocalization Golgin Hela 
ProteomicsPost-transcriptional characterization of the vertebrate aging brain sheds light on the origin of protein-transcript decoupling
Proteome-wide variation in subcellular localization using LOPIT-DC in killifish brain aging.
ORGANISM(S): Nothobranchius Furzeri (ncbitaxon:105023) 
2023-05-11 | MSV000091916 | MassIVE
Sort   by:  
 Page size