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ProteomicsLOPIT-DC subcellular map of U-2 OS cells
Generation of a high-resolution subcellular localisation map for the proteome of the human cancer cell line U-2 OS, using the newly developed LOPIT-DC method. Comparison of the results generated using LOPIT-DC with data generated using the well-established hyperLOPIT method and data mining regarding...
ORGANISM(S): Homo sapiens (Human) 
2019-01-23 | PXD011254 | Pride
Lopit-dc Hyperlopit Cancer subcellular map Spatial proteomics 
ProteomicsLOPIT-DC subcellular map of U-2 OS cells
Generation of a high-resolution subcellular localisation map for the proteome of the human cancer cell line U-2 OS, using the newly developed LOPIT-DC method. Comparison of the results generated using LOPIT-DC with data generated using the well-established hyperLOPIT method and data mining regarding...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-11-23 | MSV000088434 | MassIVE
ProteomicsTHE PHARMACOLOGICAL RESCUE OF CFTR BY LUMACAFTOR (VX-809) IN THE CYSTIC FIBROSIS BRONCHIAL EPITHELIUM IS ASSOCIATED WITH AN EXTENSIVE REORGANIZATION OF MITOCHONDRIA.
Cystic Fibrosis (CF) is a genetic disorder CF is caused by mutations of the gene encoding for the cystic fibrosis transmembrane conductance regulator protein (CFTR), a transmembrane anion channel expressed at the apical membrane of several organs, including the epithelial cells of the airway. CFTR m...
ORGANISM(S): Homo sapiens (Human) 
2022-08-11 | PXD028393 | Pride
Lopit-dc Spatial proteomics Vx-809 Cfbe41o- cells Cystic fibrosis 
ProteomicsSpatial proteomics defines the content of trafficking vesicles captured by golgin tethers
Intracellular traffic between compartments of the secretory and endocytic pathways is mediated by vesicle-based carriers. The proteomes of carriers destined for many organelles are ill-defined because the vesicular intermediates are transient, low-abundance and difficult to purify. Here, we combine ...
ORGANISM(S): Homo sapiens (Human) 
2020-12-01 | PXD018110 | Pride
Lopit-dc Organell protein relocalization Golgin Hela 
ProteomicsPost-transcriptional characterization of the vertebrate aging brain sheds light on the origin of protein-transcript decoupling
Proteome-wide variation in subcellular localization using LOPIT-DC in killifish brain aging.
ORGANISM(S): Nothobranchius Furzeri (ncbitaxon:105023) 
2023-05-11 | MSV000091916 | MassIVE
UnknownCombining LOPIT with differential ultracentrifugation for high-resolution spatial proteomics.
Not available
S-EPMC6338729 | biostudies-literature
UnknownCFTR Rescue by Lumacaftor (VX-809) Induces an Extensive Reorganization of Mitochondria in the Cystic Fibrosis Bronchial Epithelium.
Not available
S-EPMC9222197 | biostudies-literature
ProteomicsProteotranscriptomic assisted gene annotation and spatial proteomics of the lepidopteran model species Bombyx moriProteotranscriptomic assisted gene annotation and spatial proteomics of the lepidopteran model species Bombyx mori
We combined transcriptomics and proteomics to perform genome-free de novo gene annotation in Bombyx mori.
ORGANISM(S): Bombyx mori (Silk moth) 
2020-09-16 | PXD014626 | Pride
Spatial proteomics  transcriptomics  gene annotation 
Genomics
Proteotranscriptomics assisted gene annotation of Bombyx mori
PRJNA554660 | ENA
ProteomicsLocalisation of Organelle Proteins using Data-Independent Acquisition (DIA-LOP)
Subcellular localisation within the proteome fundamentally influences cellular processes, however the development of high-throughput techniques to allow proteome-wide mapping of the cell has proven difficult. Here we present DIA-LOP, an approach capable of high-throughput spatial proteome mapping wi...
ORGANISM(S): Homo sapiens (Human) 
2025-09-29 | PXD063082 | Pride
Human Lc-msms Dia Diapasef Dda 
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