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Recombinant human leptin (metreleptin) reduces hepatic lipid content in patients with lipodystrophy and overweight patients with non-alcoholic fatty liver disease and relative hypoleptinemia independent of its anorexic action. In rodents, leptin signaling in the brain increases very-low-density lipo...
2023-06-07 | MTBLS4231 | MetaboLights

Epidemiological studies have estimated a cumulative prevalence of PD of greater than 1 per thousand. When prevalence is limited to senior populations, this proportion increases nearly 10-fold. The estimated genetic risk ratio for PD is approximately 1.7 (70% increased risk for PD if a sibling...

Microarray analysis of gene expression regulation in LS174T cells transduced with either ERK-dimerization inhibitory peptide or control.
ORGANISM(S): Homo sapiens 
This study identifies gene expression changes in murine hearts after TAC surgery and in response to gene therapy with ERK-dimerization inhibitory peptide
ORGANISM(S): Mus musculus 
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