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ModelsMoreno2019 - Stochastic model of G1 arrest due to proteostasis decline delimits replicative lifespan in yeast
This model is described within the paper: A G1 arrest due to proteostasis decline delimits replicative lifespan in yeast David F. Moreno, Kirsten Jenkins, Sandrine Morlot, Gilles Charvin, Attila Csikász-Nagy, Martí Aldea To be implemented in Copasi. Missing Event due to difficulties in SBML conver...
2019-11-29 | MODEL1901210001 | BioModels
UnknownImbalanced Skeletal Muscle Mitochondrial Proteostasis Causes Bone Loss.
Not available
S-EPMC11362843 | biostudies-literature
ProteomicsDivergent proteome tolerance against gain and loss of chromosome arms
How aneuploid cells tolerate chromosome arm gains or losses remains an open question. Using an isogenic human lung cell model with either 3p loss or 3q gain, combined with quantitative mass spectrometry and isotopic labeling, we reveal distinct proteostasis mechanisms for gain- and loss-type aneuplo...
ORGANISM(S): Homo sapiens (Human) 
2025-10-06 | PXD062437 | Pride
Proteostasis  gain and loss  chromosome 3  lung cancer  proteomic buffering : aneuploidy  proteomics  dynamic silac  protein degradation  protein synthesis 
GenomicsNoise exposures causing hearing loss generate proteotoxic stress and activate the proteostasis network
Noise exposures causing hearing loss generate proteotoxic stress and activate the proteostasis network
PRJNA673829 | ENA
ProteomicsUBXN1 maintains ER proteostasis and represses UPR activation by modulating translation
ER protein homeostasis (proteostasis) is essential to facilitate proper folding and maturation of proteins in the secretory pathway. Loss of ER proteostasis can lead to the accumulation of misfolded or aberrant proteins in the ER and triggers the unfolded protein response (UPR). Here we find that th...
ORGANISM(S): Homo sapiens (Human) 
2024-06-16 | PXD043686 | Pride
Ubxn Tmt Upr Er stress Proteostasis 
GenomicsRegulation of germline proteostasis by insulin/IGF-1 signaling
Regulation of germline proteostasis by insulin/IGF-1 signaling
PRJNA1078387 | ENA
UnknownGain and loss of the centrosomal protein taxilin-beta influences cardiac proteostasis and stress.
Not available
S-EPMC12465015 | biostudies-literature
GenomicsIdentification of a link between splicing and endoplasmic reticulum proteostasis
Identification of a link between splicing and endoplasmic reticulum proteostasis
PRJNA1068596 | ENA
UnknownUbr1-induced selective endophagy/autophagy protects against the endosomal and Ca2+-induced proteostasis disease stress.
Not available
S-EPMC8888484 | biostudies-literature
UnknownLoss of Fis1 impairs proteostasis during skeletal muscle aging in Drosophila.
Not available
S-EPMC8208795 | biostudies-literature
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