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MetabolomicsIntegrative Modeling of Quantitative Plasma Lipoprotein, Metabolic, and Amino Acid Data Reveals a Multiorgan Pathological Signature of SARS-CoV-2 Infection
The metabolic effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on human blood plasma were characterized using multi-platform metabolic phenotyping with Nuclear Magnetic Resonance (NMR) spectroscopy and liquid chromatography-mass spectrometry (LC-MS). Quantitative mea...
2021-01-29 | MTBLS2014 | MetaboLights
MetabolomicsA red wine intervention does not modify plasma trimethylamine N-oxide but is associated with broad shifts in the plasma metabolome and gut microbiota composition

BACKGROUND: Gut microbiota profiles are closely related to cardiovascular diseases through mechanisms that include the reported deleterious effects of metabolites, such as trimethylamine N-oxide (TMAO), which have been studied as diagnostic and therapeutic targets. Moderate red ...

2024-05-09 | MTBLS310 | MetaboLights
UnknownMpox virus and transmission through sexual contact: Defining the research agenda.
Not available
S-EPMC9888714 | biostudies-literature
TranscriptomicsTranscription profiling of four mouse tissues following acute caloric restriction
Multi-tissue transcriptional response following acute caloric restriction in mice.
ORGANISM(S): Mus musculus 
2007-05-17 | E-MEXP-748 | biostudies-arrayexpress
TranscriptomicsTranscriptional characterization of maize roots in response to urea and nitrate
Although urea is the most used nitrogen fertilizer worldwide, little is known on the capacity of crop plants to use urea per se as a nitrogen source for development and growth. To date, the molecular and physiological bases of its transport have been investigated only in a limited number of species....
ORGANISM(S): Zea mays 
2015-03-02 | E-GEOD-53102 | biostudies-arrayexpress
TranscriptomicsThe role of membrane fluidity in low temperature perception
The aim of this work is to investigate whether A. thaliana senses low temperature by perceiving changes in membrane fluidity. To this end, we have performed an experiment to test whether mutant or transgenic plants with altered membrane lipid composition, regulate their gene expression in the same m...
ORGANISM(S): Arabidopsis thaliana 
2013-08-30 | E-GEOD-50435 | biostudies-arrayexpress
MetabolomicsNon-targeted in vitro metabolomics for proteome-scale identification of novel enzymes in Escherichia coli
Many yet undiscovered enzymes still limit our understanding of metabolism. Here, we develop a high-throughput mass spectrometry approach to comprehensively profile proteome-scale protein collections for in vitro enzymatic activity. Overexpressed or purified proteins are incubated in a supplemented m...
2016-01-11 | MTBLS373 | MetaboLights
UnknownDistinct histopathological features are associated with molecular subtypes and outcome in low grade serous ovarian carcinoma.
Not available
S-EPMC10175560 | biostudies-literature
TranscriptomicsTranscription profiling of Arabidopsis mutant or transgenic plants with altered membrane lipid composition to investigate the role of membrane fluidity in low temperature perception
The aim of this work is to investigate whether A. thaliana senses low temperature by perceiving changes in membrane fluidity. To this end, we have performed an experiment to test whether mutant or transgenic plants with altered membrane lipid composition, regulate their gene expression in the same m...
ORGANISM(S): Arabidopsis thaliana 
2008-02-15 | E-NASC-66 | biostudies-arrayexpress
ProteomicsMolecular mechanism for selection and control of HIV-1 escape virus by T cells and KIR2DL2+ NK cells
NK cells and CD8+ T cells both contribute to HIV-1 control. These cells not only suppress HIV-1 replication, but also select HIV-1 escape mutant viruses. Most viruses bearing T cell escape mutations are expected to remain susceptible to NK cell suppression, but their control by NK cells is unclear. ...
ORGANISM(S): Homo sapiens (Human) Human immunodeficiency virus 1 
2025-08-29 | PXD058766 | Pride
Hiv Nk cells Hla-c Kir 
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