Sort   by:  
 Page size 
MetabolomicsMetabolic profiling of plasma collected from Peromyscus leucopus and Mus musculus following LPS treatment
Not available
ORGANISM(S): Mus musculus;Peromyscus leucopus 
ST001654 | MetabolomicsWorkbench
MetabolomicsNorbergenin prevents LPS-induced inflammatory responses in macrophages through inhibiting NFkB, MAPK and STAT3 activation and blocking metabolic reprogramming

Inflammation is thought to be a key cause of many chronic diseases and cancer. However, current therapeutic agents to control inflammation have limited long-term use potential due to various side-effects. This study aimed to examine norbergenin, a constituent of traditional anti-inflammatory reci...

2023-04-06 | MTBLS7127 | MetaboLights
MetabolomicsBerberine improves intestinal barrier and cognitive impairment by remodeling intestinal microbiota in C57BL/6 septic mice induced by LPS
After feeding LPS induced C57BL/6 septic mice with berberine, we performed behavioral, HE staining, ELISA, western blot, metagenomic sequencing of gut microbiota and untargeted metabolomics analysis to evaluate the effects of berberine on septic mice.
2026-06-17 | MTBLS14775 | MetaboLights
TranscriptomicsTranscription profiling of fibroblast-like synovial cells from normal adult horse following treatment with hyaluronan and challenged with lipopolysaccharide
Greater than 95% confluent (Day 0) fibroblast-like synovial cells from the hind limbs (pelvic limb) of normal adult horses were allocated in triplicate to one of 4 groups:

(group 1) unchallenged;
(group 2) LPS-challenged;
(group 3) LPS-challenged following pre-treatment and susta...
ORGANISM(S): Equus caballus 
2007-01-10 | E-MEXP-940 | biostudies-arrayexpress
TranscriptomicsmiRNA array for LPS-activated tnc+/+ and tnc-/- macrophages
Endogenous molecules generated upon pathogen invasion or tissue damage serve as danger signals that activate host defence, however their precise immunological role remains unclear. Tenascin-C is an extracellular matrix glycoprotein that is specifically induced upon injury and infection. We have show...
ORGANISM(S): Mus musculus 
2012-10-18 | E-GEOD-41584 | biostudies-arrayexpress
TranscriptomicsEffect of LPS and LPS-binding protein treatment on RAW 264.4 cells
All samples were gathered from mouse RAW 264.7 cells (macrophages). Control total RNA was extracted from untreated RAW 264.7 cells cultured for either 1, 2, 4, 8, 16 or 48 hours. Test total RNA was extracted from lipopolysaccharide (100ng/ml) and lipopolysaccharide-binding protein (100pM) treated RA...
ORGANISM(S): Mus musculus 
2004-03-04 | E-GEOD-1098 | biostudies-arrayexpress
TranscriptomicsCompare RNA profile between LPS+CPN and LPS+CPN+GGOH treated peritoneal macrophages
To find out genes regulated by geranylgeraniol (GGOH) treatment in peritoneal macrophage, we compared gene expression of cells treated with 200ng ml LPS and 250 micromolar compactin versus 200ng ml LPS, 250 micromolar compactin and 100micromolar GGOH. To find out upregulated or downregulated genes r...
ORGANISM(S): Mus musculus 
2013-11-12 | E-GEOD-48646 | biostudies-arrayexpress
MetabolomicsMouse macrophages from bone marrow treatment
Not available
ORGANISM(S): Mus musculus 
ST000174 | MetabolomicsWorkbench
TranscriptomicsNFAT-mediated gene expression response to LPS in murine dendritic cells and macrophages
This SuperSeries is composed of the following subset Series: GSE15718: Gene expression in dendritic cells stimulated with LPS in conditions allowing or inhibiting NFAT activation GSE15720: Apoptosis genes specifically modulated by NFAT in LPS-activated dendritic cells GSE15721: Gene expression in ma...
ORGANISM(S): Mus musculus 
2010-03-03 | E-GEOD-15759 | biostudies-arrayexpress
ProteomicsLPS Tolerance inhibits cellular respiration and induces global changes in the secretome
Inflammatory response plays an essential role in the resolution of infections. However, inflammation can be detrimental to the organism and cause irreparable damage, for example during sepsis, when a “cytokine storm” can lead to multiple organ failure and often ends in death. One of the strongest tr...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-09 | PXD021925 | Pride
Macrophages Raw 264.7 Secretome Lps tolerance 
Sort   by:  
 Page size