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ProteomicsMouse，oocyte ，LC-MS/MS-mRBPome capture of oocytes identifies the RNA-binding protein LSM14B, an essential regulator of meiosis in mouse oocytes
proteins from immunoprecipitation (IP) of LSM14B indentified by mass spectrometry
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD034185 | Pride
Oocyte Mouse Ip Lsm14b 
ProteomicsLSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance
Fully grown oocytes remain transcriptionally quiescent, yet many maternal mRNAs are synthesized and retained in growing oocytes. We now know that maternal mRNAs are stored in a structure called the mitochondria associated ribonucleoprotein domain (MARDO). But the components and functions of MARDO re...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-17 | PXD042761 | Pride
Lsm14b  oocyte meiotic maturation  mrna storage 
GenomicsLoss of LSM14b affects the meiosis process of mouse oocytes
Loss of LSM14b affects the meiosis process of mouse oocytes
PRJNA814995 | ENA
ProteomicsMus_Oocyte_LC-MS/MS-mRBPome capture of oocytes identifies the RNA-binding protein LSM14B, an essential regulator of meiosis in mouse oocytes
A quantitative mass-spectrometry-based proteome profiles of oocytes in WT and Lsm14b KO mouse
ORGANISM(S): Mus musculus (Mouse) 
2023-07-20 | PXD034070 | Pride
Wt and lsm14b ko Oocyte Mouse Lc-ms/ms 
UnknownLSM14B controls oocyte mRNA storage and stability to ensure female fertility.
Not available
S-EPMC10425512 | biostudies-literature
UnknownLSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance.
Not available
S-EPMC10681746 | biostudies-literature
TranscriptomicsLoss of LSM14b affects the meiosis process of mouse oocytes
RNA-Seq can comprehensively and quickly obtain almost all transcripts and information of specific cells in rustic states.Here,we compared up-regulated genes in GV and MII oocytes from LSM14b deficient mice and wild-type mice by RNA-Seq,highlighting the important role of LSM14b in meiosis of mouse oo...
ORGANISM(S): Mus musculus 
2023-12-01 | GSE198414 | GEO
GenomicsLSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance
LSM14B is essential for oocyte meiotic maturation by regulating maternal mRNA storage and clearance
PRJNA967243 | ENA
TranscriptomicsProfiling of RNA-binding protein LSM14B target sites in oocyte by LACE-seq
RNA-binding proteins (RBPs) have essential functions during oocyte development. In order to explore the regulatory role of RNA-binding protein LSM14B in oocyte, we determined the binding sites and regulatory mechanisms for LSM14B by LACE-seq.
ORGANISM(S): Mus musculus 
2023-09-08 | GSE206190 | GEO
UnknownLSM14B is an Oocyte-Specific RNA-Binding Protein Indispensable for Maternal mRNA Metabolism and Oocyte Development in Mice.
Not available
S-EPMC10288277 | biostudies-literature
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