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TranscriptomicsPLZF acts as a regulator of cell-cycle genes, restricting hematopoietic stem cell proliferation and prevents hematopoietic stem cell aging.
To uncover gene programs that are regulated by PLZF in the early hematopoietic compartment, we performed micro array-based gene expression analysis of wild-type (WT) or PLZF-mutant (Zbtb16lu/lu) KSLs. DNA-microarrays were used to define and compare the transcriptional profiles of KSL cells isolated...
ORGANISM(S): Mus musculus 
2016-06-29 | E-MTAB-3682 | biostudies-arrayexpress
UnknownDiscovery of markers of exposure specific to bites of Lutzomyia longipalpis, the vector of Leishmania infantum chagasi in Latin America.
Not available
S-EPMC2843637 | biostudies-literature
UnknownSulfur-Decorated Ni-N-C Catalyst for Electrocatalytic CO2 Reduction with Near 100 % CO Selectivity.
Not available
S-EPMC9804562 | biostudies-literature
TranscriptomicsAffymetrix SNP array data for NSCLC and CRC
Cancer is a heterogeneous disease caused by genomic aberrations and characterized by significant variability in clinical outcome and response to therapies. Several subtypes of common cancer types have been identified based on alterations of individual cancer genes, such as HER2, EGFR, and others. Ho...
ORGANISM(S): Homo sapiens 
2010-08-06 | E-GEOD-20481 | biostudies-arrayexpress
UnknownPhase II study of everolimus and letrozole in patients with recurrent endometrial carcinoma.
Not available
S-EPMC4348638 | biostudies-literature
TranscriptomicsSingle-cell RNA-sequencing of immune cells in (1) mouse Renca model treated with anti-CSF1R and (2) mouse MC38 model treated with anti-CD40
Single-cell RNA sequencing (scRNA-seq) is a powerful tool for defining cellular diversity in tumors, but its application towards dissecting mechanisms underlying immune-modulating therapies is scarce. We performed scRNA-seq analyses on immune cells in mouse tumors and identified specific macrophage ...
ORGANISM(S): Mus musculus 
2020-02-23 | E-MTAB-8832 | biostudies-arrayexpress
UnknownHigh-Temporal-Resolution smFISH Method for Gene Expression Studies in Caenorhabditis elegans Embryos.
Not available
S-EPMC10619480 | biostudies-literature
UnknownHydrogel-based biocontainment of bacteria for continuous sensing and computation.
Not available
S-EPMC9269716 | biostudies-literature
MetabolomicsIntegrated Analyses of the Gut Microbiota, Intestinal Permeability and Serum Metabolome Phenotype in Rats with Alcohol Withdrawal Syndrome
The etiology of alcohol dependence is not completely understood. Increasing evidence reveals that gut microbiota dysbiosis is associated with certain psychiatric disorders, including alcoholism, through the 'microbiota-gut-brain' axis. The aims were to evaluate the effect of alcohol abuse on the gut...
2021-07-30 | MTBLS2688 | MetaboLights
TranscriptomicsComparative transcriptomics and metabolomic analysis of fenofibrate and fish oil treatments in mice
Elevated circulating triglycerides, which are considered a risk factor for cardiovascular disease, can be targeted by treatment with fenofibrate or fish oil. To gain insight into underlying mechanisms, we carried out a comparative transcriptomics and metabolomics analysis of the effect of 2 week tre...
ORGANISM(S): Mus musculus 
2011-10-07 | E-GEOD-32706 | biostudies-arrayexpress
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