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TranscriptomicsExpression analysis of human melanoma short-term culture WM451-Lu harvested after lentiviral infection with a GFP (control) or SETDB1 (experimental) viral vector
Investigation of expression differences induced by expression of the histone methyltransferase SETDB1 in human melanoma short-term culture WM451-Lu. A six-chip study using total RNA prepared from WM451-Lu melanoma short-term cultures infected with either a lentivirus encoding GFP (control) or SETDB1...
ORGANISM(S): Homo sapiens 
2011-01-07 | E-GEOD-26371 | biostudies-arrayexpress
Unknown177 Lu-rhPSMA-10.1 Induces Tumor Response in a Patient With mCRPC After PSMA-Directed Radioligand Therapy With 177 Lu-PSMA-I&T.
Not available
S-EPMC9988218 | biostudies-literature
TranscriptomicsRNA-Seq analysis of subcutaneous patient-derived neuroblastoma xenografts (LU-NB-3R): Comparison of BAY390, A967079, and vehicle controls
Neuroblastoma (NB) is a pediatric cancer characterized by significant heterogeneity and poor prognosis, particularly in high-risk cases with MYCN amplification. Understanding the molecular response of neuroblastoma to different treatments can provide valuable insights into potential therapeutic stra...
ORGANISM(S): Homo sapiens 
2026-04-01 | E-MTAB-15002 | biostudies-arrayexpress
TranscriptomicsmicroRNA Profiling in Wilms Tumors and Kidney Tissues
The IGF2-intronic miR-483 selectively enhances transcription from IGF2 fetal promoters and enhances tumorigenesis. The expression levels of microRNAs were profiled in 20 human Wilms tumor samples (WT), 3 human normal adult kidney samples (AK) and 5 human fetal kidney samples (FK) using a Luminex bea...
ORGANISM(S): Homo sapiens 
2013-12-22 | E-GEOD-50505 | biostudies-arrayexpress
TranscriptomicsRNA-seq of tumor organoids from patient-derived xenograft (PDX, LU-NB-2) of high-risk, MYCN-amplified neuroblastoma treated with prochlorperazine (PCZ), pitavastatin (PIT), the combination of both drugs, and untreated controls.
Neuroblastoma (NB) is a pediatric cancer characterized by significant heterogeneity and poor prognosis, especially in high-risk cases with MYCN amplification. Understanding the molecular response of neuroblastoma to different treatments can provide insights into potential therapeutic strategies. The...
2025-05-25 | E-MTAB-14846 | biostudies-arrayexpress
TranscriptomicsRNA-seq of subcutaneous patient-derived neuroblastoma xenografts (LU-NB-1) - Comparison of Prochlorperazine + Pitavastatin (PCZ+PIT) combination alone to one combined with standard-of-care COJEC protocol (PCZ+PIT+COJEC)
Neuroblastoma (NB) is a pediatric cancer characterized by significant heterogeneity and poor prognosis, specially in high-risk cases with MYCN amplification. Understanding the molecular response of neuroblastoma to different treatments can provide insights into potential therapeutic strategies. The ...
ORGANISM(S): Homo sapiens 
2025-07-30 | E-MTAB-14902 | biostudies-arrayexpress
MetabolomicsIntegrated microbiome-metabolome-genome axis data of Laiwu and Lulai pigs
Excessive fat deposition can trigger metabolic diseases, and it is crucial to identify factors that can break the link between fat deposition and metabolic diseases. Healthy obese Laiwu pigs (LW) are high in fat content but resistant to metabolic diseases. In this study, we compared the fecal microb...
2023-04-20 | MTBLS3977 | MetaboLights
GenomicsTET1 is a maintenance DNA demethylase that prevents methylation spreading in adult cells [DREAM]
We report that full length TET1 (TET1-FL) overexpression fails to induce global DNA demethylation in HEK293T cells. The preferential binding of TET1-FL to hypomethylated CpG islands (CGIs) through its CXXC domain leads to its inhibited 5-hydroxymethylcytosine (5hmC) production as methylation level i...
ORGANISM(S): Homo sapiens 
2014-06-04 | E-GEOD-44038 | biostudies-arrayexpress
UnknownRepurposed Effect of 177Lu-DOTATATE in the Treatment of Mantle Cell Lymphoma.
Not available
S-EPMC9599960 | biostudies-literature
MetabolomicsA novel strategy for mining and identification of acylcarnitines using data-independent-acquisition (DIA) based retention time prediction modeling and pseudo-characteristic fragmentation ions matching
It is a challenging work to screen, identify, and quantify acylcarnitines in complex biological samples. A method, based on the retention time (RT) prediction and data-independent acquisition strategies, was proposed for the large-scale identification of acylcarnitines using liquid chromatography co...
2021-10-06 | MTBLS1932 | MetaboLights
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