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MetabolomicsAge-, sex- and proximal-distal-resolved multi-omics identifies regulators of intestinal aging in non-human primates.

The incidence of intestinal diseases increases with age, but the regulators of gut aging and the molecules linking gut aging and diseases remain largely unknown. By profiling the transcriptome, proteome, phosphoproteome and metabolome of 104 Macaca fascicularis large intestinal tissues, ...

2023-12-14 | MTBLS7612 | MetaboLights
UnknownA global analysis of CNVs in Chinese indigenous fine-wool sheep populations using whole-genome resequencing.
Not available
S-EPMC7825165 | biostudies-literature
UnknownMultiple forms of vitamin B6 regulate salt tolerance by balancing ROS and abscisic acid levels in maize root.
Not available
S-EPMC10441934 | biostudies-literature
UnknownGenome-wide association studies detects candidate genes for wool traits by re-sequencing in Chinese fine-wool sheep.
Not available
S-EPMC7893944 | biostudies-literature
UnknownNeddylation of Coro1a determines the fate of multivesicular bodies and biogenesis of extracellular vesicles.
Not available
S-EPMC8500273 | biostudies-literature
UnknownFas signaling-mediated TH9 cell differentiation favors bowel inflammation and antitumor functions.
Not available
S-EPMC6606754 | biostudies-literature
ProteomicsProteome data in response to selenium
One-year-old tea plant cuttings (C. sinensis cv. ‘Zhongcha 108’) were grown in a greenhouse under a 12-h photoperiod and at 22 °C and 70% RH. After the adventitious roots emerged, the cuttings were transferred to fresh solution without Se or supplemented with 5 μM Na2SeO3 or 5 μM Na2SeO4. After 48 h...
ORGANISM(S): Camellia Sinensis 
2022-01-13 | PXD030944 |
ProteomicsSpatial-temporal protein interactome profiling via condensation enhanced crosslinking
MS data for the verification of metabolic incorporation of δ-photolysine, calculation for the crosslinking distance by DegP crosslinking, and the proteomics analysis for the dynamic direct interactome of NPM1 as well as the SG-specific interactomes of SARS-CoV-2 Nucleocapsid protein and YTHDF1/2.
ORGANISM(S): Homo Sapiens Escherichia Coli Severe Acute Respiratory Syndrome Coronavirus 2 
2024-09-11 | PXD052099 |
ProteomicsAge-, sex- and proximal–distal-resolved multi-omics identifies regulators of intestinal aging in non-human primates
To determine the molecular landscape of large intestinal aging, we collected 104 pieces of fresh large intestinal tissue from 26 Macaca fascicularis and performed age-, location-, and sex-resolved multi-omics analyses, including transcriptomics, proteomics, phosphoproteomics and metabolomics.
ORGANISM(S): Macaca Fascicularis Fascicularis 
2024-01-18 | PXD039361 |
ProteomicsProteomics data of colorectal cancer
Paired tumor and distant normal tissues from a cohort of 104 colon cancer patients were collected at West China Hospital and snap-frozen in liquid nitrogen. The informed consent forms were signed by the participants or their family members.
ORGANISM(S): Homo Sapiens 
2023-01-11 | PXD039360 |
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