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ProteomicsAcetylome analysis of HepG2 cells after treatment with PBS or LukS-PV
We previously reported that LukS-PV, a component of Panton-Valentine interleukin (PVL), has anti-leukaemic activity, inducing differentiation, increasing apoptosis and inhibiting proliferation of acute myeloid leukaemia (AML) cells. In addition, our study showed that LukS-PV could inhibit the progre...
ORGANISM(S): Homo sapiens (Human) 
2026-01-02 | PXD057287 | Pride
Luks-pv  hepg2  acetylome analysis  lc-ms/ms 
UnknownLukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.
Not available
S-EPMC9175482 | biostudies-literature
UnknownThe anticancer effect of recombinant LukS-PV protein and silver nanoparticles loaded with this protein.
Not available
S-EPMC10250288 | biostudies-literature
UnknownLukS-PV targeting C5aR inhibits EMT in hepatocellular carcinoma via the BCL6/HDAC6/HSPD1 axis.
Not available
S-EPMC12936196 | biostudies-literature
UnknownLukS-PV Induces Apoptosis via the SET8-H4K20me1-PIK3CB Axis in Human Acute Myeloid Leukemia Cells.
Not available
S-EPMC8565356 | biostudies-literature
UnknownToxin protein LukS-PV targeting complement receptor C5aR1 inhibits cell proliferation in hepatocellular carcinoma via the HDAC7-Wnt/β-catenin axis.
Not available
S-EPMC11910327 | biostudies-literature
UnknownQuantitative proteomic analysis reveals that Luks-PV exerts antitumor activity by regulating the key proteins and metabolic pathways in HepG2 cells.
Not available
S-EPMC7028286 | biostudies-literature
Genomics
LukS-PV induces AML cell apoptosis by targeting SET8.
PRJNA767433 | ENA
UnknownEngineering of the LukS-PV and LukF-PV subunits of Staphylococcus aureus Panton-Valentine leukocidin for diagnostic and therapeutic applications.
Not available
S-EPMC3870988 | biostudies-literature
Genomics
RNA-seq of HepG2 cells after treatment with PBS or LukS-PV
PRJNA1179664 | ENA
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