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ProteomicsSelective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites
The centrosome is the master orchestrator of mitotic spindle formation and chromosome segregation in animal cells. Centrosome abnormalities are frequently observed in cancer, but little is known of their origin and about pathways affecting centrosome homeostasis. Here we show that autophagy preserve...
ORGANISM(S): Homo sapiens (Human) 
2019-09-12 | PXD014829 | Pride
Centrosome Selective autophagy Centrosome fragmentation Gabarap Mitosis Cep131 Autophagy Centriolar satellites Pcm1 
TranscriptomicsPrdm5 suppresses ApcMin-driven intestinal adenomas and regulates monoacylglycerol lipase expression
PRDM proteins are tissue specific transcription factors often deregulated in diseases, particularly in cancer where different members have been found to act as oncogenes or tumor suppressors. PRDM5 is a poorly characterized member of the PRDM family for which several studies have reported a high fre...
ORGANISM(S): Mus musculus 
2013-05-11 | E-GEOD-46821 | biostudies-arrayexpress
UnknownThe effects of lowering LDL cholesterol with simvastatin plus ezetimibe in patients with chronic kidney disease (Study of Heart and Renal Protection): a randomised placebo-controlled trial.
Not available
S-EPMC3145073 | biostudies-literature
UnknownObservation of quantum entanglement with top quarks at the ATLAS detector.
Not available
S-EPMC11410654 | biostudies-literature
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