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ProteomicsLarge Aging Neutrophil-Derived Vesicles (LAND-Vs) Perpetuate Host Anti-Inflammatory Response to Facilitate Inflammation Resolution
Precise regulation of the duration and extent of inflammation is crucial for balancing pathogen elimination and preventing tissue damage. The mechanisms underlying inflammation resolution are not yet fully understood. Here, we reveal that neutrophils, typically known for their pro-inflammatory role ...
ORGANISM(S): Homo sapiens (Human) 
2026-03-23 | PXD048609 | Pride
Land-v Human neutrophils Human vesicle 
ProteomicsIdentification of gasderminD interacting proteins by mass spectrometry
Gasdermin D (GSDMD)-mediated macrophage pyroptosis plays a critical role in inflammation and host defense. Plasma membrane perforation elicited by caspase-cleaved GSDMD N-terminal domain (GSDMD-NT) triggers membrane rupture and subsequent pyroptotic cell death, resulting in release of pro-inflammato...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD039133 | Pride
Fasn Palmitoylation Gsdmd Gasdermin d Immunoprecipitation Pyroptosis  lc-msms 
MetabolomicsThe trans-omics landscape of COVID-19
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
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