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ProteomicsHEK293T cells were transfected with Flag-tagged NLRP3 treated with or without nigericin (10 μM, 1 h).
In order to identificate NLRP3 acetylation, we utilized an acetylproteomic approach to identify the acetylation sites within NLRP3. We first reconstituted the NLRP3 inflammasome in HEK293T cells by co-transfected with plasmids encoding NLRP3, ASC, Caspase-1 and Pro-IL-1β, then stimulated the genetic...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-25 | PXD041763 | Pride
Hek293tcells， nlrp3 
TranscriptomicsA systems approach to delineate functions of YAP family members
Duplication of genes encoding transcription factors plays an essential role in driving phenotypic variation. Because regulation can occur at multiple levels, it is often difficult to discern how each duplicated factor achieves its regulatory specificity. In these cases, a systems approach may distin...
ORGANISM(S): Saccharomyces cerevisiae 
2008-02-03 | E-GEOD-10146 | biostudies-arrayexpress
ProteomicsStructure and mechanism of CSP secretion pump of ComA for Quorum sensing
Cross-linking MS data for 1) ComA Apo form and 2) ComA +ATP form. Purified proteins were cross-linked with DSSO, digested with either trypsin or chymotrypsin, and acquired by MS2-MS3 acquisition method. 2 technical replicates were acquired for each digested sample.
ORGANISM(S): Cellular Organisms 
2023-08-31 | PXD038058 | JPOST Repository
UnknownEffectiveness of a Water Intake Program at the Workplace in Physical and Mental Health Outcomes.
Not available
S-EPMC8998380 | biostudies-literature
ProteomicsIntact Mass analysis of class III lanthipeptide PneA
Intact Mass analysis of PneA under various modification states
ORGANISM(S): Streptococcus Pneumoniae Pt8114 
2024-08-13 | PXD050940 |
UnknownInfluence of Dislocations on the Refractive Index of AlN by Nanoscale Strain Field.
Not available
S-EPMC6542867 | biostudies-literature
UnknownGeneration of tooth-like structures from integration-free human urine induced pluripotent stem cells.
Not available
S-EPMC4230506 | biostudies-literature
ProteomicsIntegrated proteomic and metabolomic analyses of the mitochondrial neurodegenerative disease MELAS
MELAS (mitochondrial encephalomyopathy, lactic acidosis, stroke-like episodes) is a progressive neurodegenerative disease caused by pathogenic mitochondrial DNA variants. The pathogenic mechanism of MELAS remains enigmatic due to the exceptional clinical heterogeneity and the obscure genotype-phenot...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-10-16 | MSV000088237 | MassIVE
TranscriptomicsMicroRNAome of porcine prenatal and postnatal development.
Sus scrofa (pig, or swine) is one of the most important economic animals and a close biological model for complex human diseases such as obesity and diabetes. It is therefore utterly important to decode the porcine microRNAome (miRNAome) as in the literature only a small portion of it is known. In t...
ORGANISM(S): Sus scrofa 
2010-02-27 | E-GEOD-17885 | biostudies-arrayexpress
ProteomicsData indpendent acquisition (DIA) proteomics Analysis of Tobacco Root Tip
Protein expression profiling of root tip of tobacco hybrids and parental was analyzed by data indpendent acquisition proteomics
ORGANISM(S): Nicotiana Tabacum 
2021-09-18 | PXD028624 |
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