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MetabolomicsPlasma metabolome alteration in dairy cows with left displaced abomasum before and after surgical correction
Left displaced abomasum (LDA) leads to substantial changes in the metabolism of dairy cows. Surgical correction of LDA can rapidly improve the health of cows; however, changes in metabolism following surgery are rarely described. To investigate the changes of plasma metabolome in cows with LDA befor...
2022-08-17 | MTBLS4126 | MetaboLights
MetabolomicsAltered Fecal Microbiome and Correlations of the Metabolome with Plasma Metabolites in Dairy Cows with Left Displaced Abomasum

Left displaced abomasum (LDA) in postpartum dairy cows contributes to significant economic losses. LDA is characterized by excessive lipolysis and insulin resistance. Although gut dysbiosis is implicated, little is known about the role of the gut microbiota in the abnormal metabolic processes of ...

2022-08-17 | MTBLS2441 | MetaboLights
UnknownThe ORB2 RNA-binding protein negatively regulates its target transcripts during the Drosophila maternal-to-zygotic transition via its functionally conserved Zinc-binding 'ZZ' domain.
Not available
S-EPMC12265677 | biostudies-literature
MetabolomicsPlasma metabolite changes in dairy cows during parturition identified using untargeted metabolomics
The metabolic responses of cows undergo substantial changes during the transition from late pregnancy to early lactation. However, the molecular mechanisms associated with these changes in physiological metabolism have not been clearly elucidated. The objective of this study was to investigate metab...
2019-08-20 | MTBLS809 | MetaboLights
UnknownA new norisoprenoid and other compounds from Fuzhuan brick tea.
Not available
S-EPMC6268391 | biostudies-literature
ProteomicsSTXBP5 prevents reannealing of autophagic cis-SNARE disassembled by NSF/αSNAP
We generated a HEK293 cell line expressing ZZ-TEV-FLAG-bait protein by Lipofectamine 3000 transfection. The expression level of bait protein is controlled to endogenous level by addition of 2 ng/mL doxycycline. Note the combined treatment of Torin1 and CQ was applied for STX17. The tandem affinity p...
ORGANISM(S): Homo sapiens (Human) 
2023-09-18 | PXD043048 | Pride
Stxbp5 Alphasnap Autophagy Disassemble Snare Nsf 
UnknownCombination of gefitinib and DNA methylation inhibitor decitabine exerts synergistic anti-cancer activity in colon cancer cells.
Not available
S-EPMC4038521 | biostudies-literature
UnknownCleavage of SQSTM1/p62 by the Zika virus protease NS2B3 prevents autophagic degradation of viral NS3 and NS5 proteins.
Not available
S-EPMC11587865 | biostudies-literature
UnknownA multigenic study on breast cancer risk associated with genetic polymorphisms of ER Alpha, COMT and CYP19 gene in BRCA1/BRCA2 negative Shanghai women with early onset breast cancer or affected relatives.
Not available
S-EPMC12160827 | biostudies-literature
UnknownIncreased miR-155 in Microglial Exosomes Following Heat Stress Accelerates Neuronal Autophagy via Their Transfer Into Neurons.
Not available
S-EPMC9132214 | biostudies-literature
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