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GenomicsRNA-seq analysis after STXBP5 overexpression or STXBP5 knockdown in HA-progerin HEK293 cells
RNA-seq analysis after STXBP5 overexpression or STXBP5 knockdown in HA-progerin HEK293 cells
PRJNA1016346 | ENA
TranscriptomicsRNA-seq analysis after STXBP5 overexpression or STXBP5 knockdown in HA-progerin HEK293 cells
Hutchinson-Gilford Progeria Syndrome (HGPS) is caused by a mutant LMNA called progerin. To determine the mechanism of STXBP5 on progerin, we over expressed STXBP5 or knocked down STXBP5 in HA-progerin HEK293 cells, then analyzed the effect on the expression of coding genes. In this study, we identif...
ORGANISM(S): Homo sapiens 
2024-09-14 | GSE243095 | GEO
UnknownThe syntaxin-binding protein STXBP5 regulates progerin expression.
Not available
S-EPMC11461833 | biostudies-literature
ProteomicsEffect of the combined loss of tomosyn (STXBP5) and tomosyn-2 (STXBP5L) on the proteome of primary mouse hippocampal neurons
Tomosyn (STXBP5) is a non-canonical SNARE protein enriched in many secretory cells and implicated in regulation of exocytosis. In neurons, loss of tomosyn affects fusion of synaptic vesicles. Here, we examined the impact of the loss of tomosyn (STXBP5) and its close paralog, tomosyn-2 (STXBP5L), on ...
ORGANISM(S): Mus musculus (Mouse) 
2022-12-19 | PXD038442 | Pride
Tomosyn Stxbp5 Swath Neuron Synapse Mouse Primaryculture 
UnknownPlatelet secretion and hemostasis require syntaxin-binding protein STXBP5.
Not available
S-EPMC4191053 | biostudies-literature
UnknownSyntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion.
Not available
S-EPMC4191049 | biostudies-literature
UnknownGinsenoside Rh2 upregulates long noncoding RNA STXBP5-AS1 to sponge microRNA-4425 in suppressing breast cancer cell proliferation.
Not available
S-EPMC8570952 | biostudies-literature
UnknownLncRNA STXBP5-AS1 suppresses stem cell-like properties of pancreatic cancer by epigenetically inhibiting neighboring androglobin gene expression.
Not available
S-EPMC7648265 | biostudies-literature
UnknownNovel Thrombotic Function of a Human SNP in STXBP5 Revealed by CRISPR/Cas9 Gene Editing in Mice.
Not available
S-EPMC5269475 | biostudies-literature
UnknownGenome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.
Not available
S-EPMC4009733 | biostudies-literature
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