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ProteomicsProteins interacting with SARS-CoV-2 envelope
HEK293T were transfected with SARS-CoV-2-E-HA for 36 h, then treated with MG132 or DMSO for 12 h prior to harvest. Co-IP assay were performed with HA beads (Roche, catalog no. 11867423001), the elution was analyzed by mass spectrum. Mass spectrum analysis were performed by the national center for pr...
ORGANISM(S): Homo Sapiens 
2023-01-01 | PXD039140 |
ProteomicsLegionella pneumophila effector LegK3 phosphorylates multiple caspases involved in apoptosis signaling
Legionella pneumophila effector Legk3 phosphorylates caspase3/7/9 under infection, transfection, or in vitro purification
ORGANISM(S): Homo Sapiens 
2024-07-20 | PXD054088 |
ProteomicsLegionella pneumophila effector LegK3 directly phosphorylates multiple caspases involved in apoptosis signaling, including Caspase-3, Caspase-7, and Caspase-9
Legionella pneumophila effector Legk3 phosphorylates caspase3/7/9 under infection, transfection, or in vitro purification condition
ORGANISM(S): Homo Sapiens 
2024-07-28 | PXD054358 |
ProteomicsThe Shigella kinase effector OspG hijacks host ubiquitin signaling to escape septin-cage entrapment
We show by unbiased phosphoproteomics that a major target of OspG is CAND1, a regulatory protein controlling the assembly of cullin-RING ubiquitin ligases (CRLs). CAND1 phosphorylation weakens its interaction with cullins, which is expected to impact a large panel of CRL E3s. Indeed, global ubiquito...
ORGANISM(S): Homo Sapiens 
2024-01-10 | PXD048447 |
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